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Published in 2017 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2016.12.021
Abstract: The medical treatment of laxoscelisms is based solely on supportive measures. Although equine antiserum for Sphingomyelinase C (SMASE) and D isomers are available, it is not used due to the risk of an anaphylactic reaction…
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Keywords:
glassy carbon;
schiff bases;
adsorbed glassy;
bases chitosan ... See more keywords
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Published in 2017 at "Genetics in Medicine"
DOI: 10.1038/gim.2017.7
Abstract: Disclaimer:This diagnostic guideline is intended as an educational resource and represents the opinions of the authors, and is not representative of recommendations or policy of the American College of Medical Genetics and Genomics (ACMG). The…
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Keywords:
sphingomyelinase;
diagnostic guideline;
acid sphingomyelinase;
sphingomyelinase deficiency ... See more keywords
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2
Published in 2023 at "Blood Advances"
DOI: 10.1182/bloodadvances.2022008392
Abstract: Key Points • Bending stress exerted on the plasma membrane by sickle hemoglobin polymerization enhances sulfatide-mediated adhesion of mature erythrocytes in SCD.• Inflammatory sphingomyelinase activity could result in abnormal adhesion and membrane damage in sickle…
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Keywords:
adhesion;
sphingomyelinase;
mature erythrocytes;
sickle mature ... See more keywords
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Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24032467
Abstract: Alterations of sphingolipids and their metabolizing enzymes play a role in various diseases. However, peripheral biomarkers for such changes are limited. Particularly, in the increasingly reported involvement of neutral sphingomyelinase (NSM) with four described isoforms…
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Keywords:
activity human;
serum;
nsm activity;
neutral sphingomyelinase ... See more keywords
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Published in 2018 at "World Journal of Hepatology"
DOI: 10.4254/wjh.v10.i2.246
Abstract: Alkaline sphingomyelinase cleaves phosphocholine from sphingomyelin, platelet-activating factor, lysophosphatidylcholine, and less effectively phosphatidylcholine. The enzyme shares no structure similarities with acid or neutral sphingomyelinase but belongs to ecto-nucleotide pyrophosphatase/phosphodiesterase (NPP) family and therefore is also…
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Keywords:
hepatobiliary diseases;
alkaline sphingomyelinase;
sphingomyelinase;
npp7 hepatobiliary ... See more keywords