Circular RNA SPI1 expression before and after induction therapy and its correlation with clinical features, treatment response, and survival of acute myeloid leukemia patients
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24835
Abstract: Circular RNA spi‐1 proto‐oncogene (circ‐SPI1) regulates cell proliferation, apoptosis, and bone marrow differentiation in acute myeloid leukemia (AML). This study aimed to assess the relationship of circ‐SPI1 expression with the clinical features, induction therapy response,… read more here.
Keywords: myeloid leukemia; circular rna; acute myeloid; spi1 ... See more keywords
Oncogenic cooperation between TCF7-SPI1 and NRAS(G12D) requires β-catenin activity to drive T-cell acute lymphoblastic leukemia
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DOI: 10.1038/s41467-021-24442-9
Abstract: Spi-1 Proto-Oncogene (SPI1) fusion genes are recurrently found in T-cell acute lymphoblastic leukemia (T-ALL) cases but are insufficient to drive leukemogenesis. Here we show that SPI1 fusions in combination with activating NRAS mutations drive an… read more here.
Keywords: cell acute; spi1; leukemia; tcf7 spi1 ... See more keywords
HilE Regulates HilD by Blocking DNA Binding in Salmonella enterica Serovar Typhimurium
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DOI: 10.1128/jb.00750-17
Abstract: ABSTRACT The Salmonella type three secretion system (T3SS), encoded in the Salmonella pathogenicity island 1 (SPI1) locus, mediates the invasion of the host intestinal epithelium. SPI1 expression is dependent upon three AraC-like regulators: HilD, HilC,… read more here.
Keywords: protein; system; salmonella; hile ... See more keywords
Comprehensive Analysis of Immune Implications and Prognostic Value of SPI1 in Gastric Cancer
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DOI: 10.3389/fonc.2022.820568
Abstract: Background The transcription factor Spi-1 proto-oncogene (SPI1, also known as PU.1) is a key regulator of signal communication in the immune system and is essential for the development of myeloid cells and lymphocytes. However, the… read more here.
Keywords: spi1 gastric; expression; analysis; expression spi1 ... See more keywords