Conformational Stability and Interplay of Helical N- and C-Terminal Domains with Implications on Major Ampullate Spidroin Assembly.
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DOI: 10.1021/acs.biomac.6b01713
Abstract: Major ampullate spidroin (MaSp) assembly starts in the abdomen of the spider, where spidroins are stored as a liquid dope at a high concentration. The dope is squeezed into the spinning duct, and assembly is… read more here.
Keywords: terminal domains; major ampullate; spidroin; spidroin assembly ... See more keywords
Overexpressed Artificial Spidroin Based Microneedle Spinneret for 3D Air Spinning of Hybrid Spider Silk.
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DOI: 10.1021/acsnano.4c08557
Abstract: Efforts have been devoted to developing strategies for converting spider silk proteins (spidroins) into functional silk materials. However, studies mimicking the exact natural spinning process of spiders encounter arduous challenges. In this paper, consistent with… read more here.
Keywords: air spinning; spidroin; silk; spider silk ... See more keywords
Spidroin striped micropattern promotes chondrogenic differentiation of human Wharton’s jelly mesenchymal stem cells
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DOI: 10.1038/s41598-022-08982-8
Abstract: Cartilage tissue engineering, particularly micropattern, can influence the biophysical properties of mesenchymal stem cells (MSCs) leading to chondrogenesis. In this research, human Wharton’s jelly MSCs (hWJ-MSCs) were grown on a striped micropattern containing spider silk… read more here.
Keywords: wharton jelly; striped micropattern; stem cells; human wharton ... See more keywords