Identification of porcine epidemic diarrhea virus variant with a large spike gene deletion from a clinical swine sample in the United States
Sign Up to like & getrecommendations! Published in 2018 at "Virus Genes"
DOI: 10.1007/s11262-018-1542-7
Abstract: Two genetically different porcine epidemic diarrhea virus (PEDV) strains have been identified in the USA: US prototype (also called non-S INDEL) and S INDEL PEDVs. In February 2017, a PEDV variant (USA/OK10240-8/2017) was identified in… read more here.
Keywords: porcine epidemic; epidemic diarrhea; deletion; spike gene ... See more keywords
A selective sweep in the Spike gene has driven SARS-CoV-2 human adaptation
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DOI: 10.1016/j.cell.2021.07.007
Abstract: The COVID-19 pandemic underscores the need to understand better animal-to-human transmission of coronaviruses and adaptive evolution within new hosts. We scanned over 182,000 SARS-CoV-2 genomes for selective sweep signatures and found a distinct footprint of… read more here.
Keywords: gene driven; selective sweep; spike gene; sars cov ... See more keywords
Targeted detection and molecular epidemiology of turkey coronavirus spike gene variants in turkeys and chickens
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Veterinary Diagnostic Investigation"
DOI: 10.1177/10406387221128610
Abstract: Turkey coronavirus (TCoV) is a member of the Avian coronavirus species with infectious bronchitis virus (IBV), which is considered to be the source of TCoV. These 2 viruses are highly similar in all regions of… read more here.
Keywords: turkey; spike gene; coronavirus; molecular epidemiology ... See more keywords
Detection of feline coronavirus spike gene mutations as a tool to diagnose feline infectious peritonitis
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Feline Medicine and Surgery"
DOI: 10.1177/1098612x15623824
Abstract: Objectives Feline infectious peritonitis (FIP) is an important cause of death in the cat population worldwide. The ante-mortem diagnosis of FIP in clinical cases is still challenging. In cats without effusion, a definitive diagnosis can… read more here.
Keywords: infectious peritonitis; feline; feline infectious; spike gene ... See more keywords
Genomic surveillance of SARS-CoV-2 Spike gene by sanger sequencing
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DOI: 10.1371/journal.pone.0262170
Abstract: The SARS-CoV-2 responsible for the ongoing COVID pandemic reveals particular evolutionary dynamics and an extensive polymorphism, mainly in Spike gene. Monitoring the S gene mutations is crucial for successful controlling measures and detecting variants that… read more here.
Keywords: spike gene; genomic surveillance; gene; surveillance sars ... See more keywords
HiSpike Method for High-Throughput Cost Effective Sequencing of the SARS-CoV-2 Spike Gene
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2021.798130
Abstract: The changing nature of the SARS-CoV-2 pandemic poses unprecedented challenges to the world's health systems. Emerging spike gene variants jeopardize global efforts to produce immunity and reduce morbidity and mortality. These challenges require effective real-time… read more here.
Keywords: cost; spike gene; high throughput; gene ... See more keywords
Isolation and Identification of a Rare Spike Gene Double-Deletion SARS-CoV-2 Variant From the Patient With High Cycle Threshold Value
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2021.822633
Abstract: Coronavirus disease 2019 (COVID-19) is an emerging life-threatening pulmonary disease caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which originated in Wuhan, Hubei Province, China, in December 2019. COVID-19 develops after close… read more here.
Keywords: double deletion; sars cov; isolation; spike gene ... See more keywords
Spike Gene Evolution and Immune Escape Mutations in Patients with Mild or Moderate Forms of COVID-19 and Treated with Monoclonal Antibodies Therapies
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DOI: 10.3390/v14020226
Abstract: We explored the molecular evolution of the spike gene after the administration of anti-spike monoclonal antibodies in patients with mild or moderate forms of COVID-19. Four out of the 13 patients acquired a mutation during… read more here.
Keywords: moderate forms; spike gene; forms covid; monoclonal antibodies ... See more keywords
Fecal Feline Coronavirus RNA Shedding and Spike Gene Mutations in Cats with Feline Infectious Peritonitis Treated with GS-441524
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DOI: 10.3390/v14051069
Abstract: As previously demonstrated by our research group, the oral multicomponent drug Xraphconn® containing GS-441524 was effective at curing otherwise fatal feline infectious peritonitis (FIP) in 18 feline coronavirus (FCoV)-infected cats. The aims of the current… read more here.
Keywords: gene mutations; spike gene; rna; rna shedding ... See more keywords