Genomic surveillance of the Lambda SARS‐CoV‐2 variant in a global phylogenetic context
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DOI: 10.1002/jmv.27889
Abstract: The massive sequencing of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) and global genomic surveillance strategies allowed the detection of many variants of concern and interest. The variant of interest Lambda (C.37), which originated in… read more here.
Keywords: lambda; spike mutations; surveillance lambda; genomic surveillance ... See more keywords
Emergence of a unique SARS‐CoV‐2 Delta sub‐cluster harboring a constellation of co‐appearing non‐Spike mutations
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28413
Abstract: Accumulation of diverse mutations across the structural and nonstructural genes is leading to rapid evolution of SARS‐CoV‐2, altering its pathogenicity. We performed whole genome sequencing of 239 SARS‐CoV‐2 RNA samples collected from both adult and… read more here.
Keywords: spike mutations; appearing non; delta sub; constellation ... See more keywords
De novo emergence of SARS‐CoV‐2 spike mutations in immunosuppressed patients
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DOI: 10.1111/tid.13914
Abstract: The continuing evolution of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) variants with decreased susceptibility to neutralizing antibodies is of clinical importance. Several spike mutations associated with immune escape have evolved independently in association with… read more here.
Keywords: cov spike; spike mutations; mutations immunosuppressed; emergence sars ... See more keywords
Development of an efficient Sanger sequencing-based assay for detecting SARS-CoV-2 spike mutations
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DOI: 10.1371/journal.pone.0260850
Abstract: Novel strains of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) harboring nucleotide changes (mutations) in the spike gene have emerged and are spreading rapidly. These mutations are associated with SARS-CoV-2 transmissibility, virulence, or resistance to… read more here.
Keywords: ssg primer; spike mutations; sars cov; primer assay ... See more keywords
Emergence and Spread of a B.1.1.28-Derived P.6 Lineage with Q675H and Q677H Spike Mutations in Uruguay
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DOI: 10.3390/v13091801
Abstract: Uruguay controlled the viral dissemination during the first nine months of the SARS-CoV-2 pandemic. Unfortunately, towards the end of 2020, the number of daily new cases exponentially increased. Herein, we analyzed the country-wide genetic diversity… read more here.
Keywords: q675h q677h; spread derived; spike mutations; emergence spread ... See more keywords
Effects of SARS-CoV-2 Omicron BA.1 Spike Mutations on T-Cell Epitopes in Mice
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DOI: 10.3390/v15030763
Abstract: T-cell immunity plays an important role in the control of SARS-CoV-2 and has a great cross-protective effect on the variants. The Omicron BA.1 variant contains more than 30 mutations in the spike and severely evades… read more here.
Keywords: omicron spike; spike mutations; cell epitopes; sars cov ... See more keywords