Association of Spike-Specific T Cells With Relative Protection From Subsequent SARS-CoV-2 Omicron Infection in Young Children
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Pediatrics"
DOI: 10.1001/jamapediatrics.2022.3868
Abstract: This cohort study investigates the risk of SARS-CoV-2 reinfection among young children with and without spike-specific T-cell responses. read more here.
Keywords: young children; specific cells; association spike; spike specific ... See more keywords
Children develop robust and sustained cross-reactive spike-specific immune responses to SARS-CoV-2 infection
Sign Up to like & getrecommendations! Published in 2021 at "Nature Immunology"
DOI: 10.1038/s41590-021-01089-8
Abstract: SARS-CoV-2 infection is generally mild or asymptomatic in children but a biological basis for this outcome is unclear. Here we compare antibody and cellular immunity in children (aged 3–11 years) and adults. Antibody responses against… read more here.
Keywords: cov infection; sars cov; spike specific; infection ... See more keywords
SARS-CoV-2 spike-specific memory B cells express higher levels of T-bet and FcRL5 after non-severe COVID-19 as compared to severe disease
Sign Up to like & getrecommendations! Published in 2021 at "PLoS ONE"
DOI: 10.1371/journal.pone.0261656
Abstract: SARS-CoV-2 infection elicits a robust B cell response, resulting in the generation of long-lived plasma cells and memory B cells. Here, we aimed to determine the effect of COVID-19 severity on the memory B cell… read more here.
Keywords: non severe; covid; spike specific; memory cells ... See more keywords
Severe and mild-moderate SARS-CoV-2 vaccinated patients show different frequencies of IFNγ-releasing cells: An exploratory study
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DOI: 10.1371/journal.pone.0281444
Abstract: Background Despite an apparent effective vaccination, some patients are admitted to the hospital after SARS-CoV-2 infection. The role of adaptive immunity in COVID-19 is growing; nonetheless, differences in the spike-specific immune responses between patients requiring… read more here.
Keywords: mild moderate; releasing cells; ifn releasing; frequencies ifn ... See more keywords
The third dose of mRNA SARS-CoV-2 vaccines enhances the spike-specific antibody and memory B cell response in myelofibrosis patients
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1017863
Abstract: Vaccination against SARS-CoV-2 using mRNA-based vaccines has been highly recommended for fragile subjects, including myelofibrosis patients (MF). Available data on the immune responsiveness of MF patients to mRNA SARS-CoV-2 vaccination, and the impact of the… read more here.
Keywords: cell response; spike specific; sars cov; third dose ... See more keywords
Persistence of spike-specific immune responses in BNT162b2-vaccinated donors and generation of rapid ex-vivo T cells expansion protocol for adoptive immunotherapy: A pilot study
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1061255
Abstract: Introduction The BNT162b2 mRNA-based vaccine has shown high efficacy in preventing COVID-19 infection but there are limited data on the types and persistence of the humoral and T cell responses to such a vaccine. Methods… read more here.
Keywords: rapid vivo; cell; memory; expansion ... See more keywords
Longitudinal monitoring of mRNA-vaccine-induced immunity against SARS-CoV-2
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1066123
Abstract: Background Worldwide vaccination campaigns significantly reduced mortality caused by SARS-CoV-2 infection and diminished the devastating effects of the pandemic. The first approved vaccines are based on novel mRNA technology and elicit potent immune responses offering… read more here.
Keywords: spike specific; fold increase; sars cov; vaccination ... See more keywords
Non-spike and spike-specific memory T cell responses after the third dose of inactivated COVID-19 vaccine
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1139620
Abstract: Background During the COVID-19 epidemic, vaccination has become the most safe and effective way to prevent severe illness and death. Inactivated vaccines are the most widely used type of COVID-19 vaccines in the world. In… read more here.
Keywords: spike; cell responses; spike specific; non spike ... See more keywords
Persons with HIV Develop Spike-Specific Lymph Node Germinal Center Responses following SARS-CoV-2 Vaccination.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of immunology"
DOI: 10.4049/jimmunol.2200920
Abstract: COVID-19 disproportionately affects persons with HIV (PWH) in worldwide locations with limited access to SARS-CoV-2 vaccines. PWH exhibit impaired immune responses to some, but not all, vaccines. Lymph node (LN) biopsies from PWH demonstrate abnormal… read more here.
Keywords: lymph node; vaccination; cov vaccination; spike specific ... See more keywords