Association of Spike-Specific T Cells With Relative Protection From Subsequent SARS-CoV-2 Omicron Infection in Young Children
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Pediatrics"
DOI: 10.1001/jamapediatrics.2022.3868
Abstract: This cohort study investigates the risk of SARS-CoV-2 reinfection among young children with and without spike-specific T-cell responses. read more here.
Keywords: young children; specific cells; association spike; spike specific ... See more keywords
Children develop robust and sustained cross-reactive spike-specific immune responses to SARS-CoV-2 infection
Sign Up to like & getrecommendations! Published in 2021 at "Nature Immunology"
DOI: 10.1038/s41590-021-01089-8
Abstract: SARS-CoV-2 infection is generally mild or asymptomatic in children but a biological basis for this outcome is unclear. Here we compare antibody and cellular immunity in children (aged 3–11 years) and adults. Antibody responses against… read more here.
Keywords: cov infection; sars cov; spike specific; infection ... See more keywords
Hypertensive Mice Have Decreased Antibody Responses to COVID-19 mRNA Vaccination in the Angiotensin II Model of Hypertension
Sign Up to like & getrecommendations! Published in 2025 at "Physiology"
DOI: 10.1152/physiol.2025.40.s1.1217
Abstract: The SARS-CoV-2 virus responsible for the COVID-19 pandemic continues to generate significant morbidity and mortality worldwide. One third of adults across the world have high blood pressure (hypertension). Hypertensive patients are twice as likely to… read more here.
Keywords: physiology; antibody; hypertensive mice; spike specific ... See more keywords
SARS-CoV-2 spike-specific memory B cells express higher levels of T-bet and FcRL5 after non-severe COVID-19 as compared to severe disease
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DOI: 10.1371/journal.pone.0261656
Abstract: SARS-CoV-2 infection elicits a robust B cell response, resulting in the generation of long-lived plasma cells and memory B cells. Here, we aimed to determine the effect of COVID-19 severity on the memory B cell… read more here.
Keywords: non severe; covid; spike specific; memory cells ... See more keywords
Severe and mild-moderate SARS-CoV-2 vaccinated patients show different frequencies of IFNγ-releasing cells: An exploratory study
Sign Up to like & getrecommendations! Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0281444
Abstract: Background Despite an apparent effective vaccination, some patients are admitted to the hospital after SARS-CoV-2 infection. The role of adaptive immunity in COVID-19 is growing; nonetheless, differences in the spike-specific immune responses between patients requiring… read more here.
Keywords: mild moderate; releasing cells; ifn releasing; frequencies ifn ... See more keywords
The third dose of mRNA SARS-CoV-2 vaccines enhances the spike-specific antibody and memory B cell response in myelofibrosis patients
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1017863
Abstract: Vaccination against SARS-CoV-2 using mRNA-based vaccines has been highly recommended for fragile subjects, including myelofibrosis patients (MF). Available data on the immune responsiveness of MF patients to mRNA SARS-CoV-2 vaccination, and the impact of the… read more here.
Keywords: cell response; spike specific; sars cov; third dose ... See more keywords
Persistence of spike-specific immune responses in BNT162b2-vaccinated donors and generation of rapid ex-vivo T cells expansion protocol for adoptive immunotherapy: A pilot study
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1061255
Abstract: Introduction The BNT162b2 mRNA-based vaccine has shown high efficacy in preventing COVID-19 infection but there are limited data on the types and persistence of the humoral and T cell responses to such a vaccine. Methods… read more here.
Keywords: rapid vivo; cell; memory; expansion ... See more keywords
Longitudinal monitoring of mRNA-vaccine-induced immunity against SARS-CoV-2
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1066123
Abstract: Background Worldwide vaccination campaigns significantly reduced mortality caused by SARS-CoV-2 infection and diminished the devastating effects of the pandemic. The first approved vaccines are based on novel mRNA technology and elicit potent immune responses offering… read more here.
Keywords: spike specific; fold increase; sars cov; vaccination ... See more keywords
Non-spike and spike-specific memory T cell responses after the third dose of inactivated COVID-19 vaccine
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1139620
Abstract: Background During the COVID-19 epidemic, vaccination has become the most safe and effective way to prevent severe illness and death. Inactivated vaccines are the most widely used type of COVID-19 vaccines in the world. In… read more here.
Keywords: spike; cell responses; spike specific; non spike ... See more keywords
Comparison of SARS-CoV-2 spike-specific IgA and IgG in nasal secretions, saliva and serum
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2024.1346749
Abstract: Introduction Several novel vaccine platforms aim at mucosal immunity in the respiratory tract to block SARS-CoV-2 transmission. Standardized methods for mucosal sample collection and quantification of mucosal antibodies are therefore urgently needed for harmonized comparisons… read more here.
Keywords: sars cov; specific iga; secretions saliva; spike specific ... See more keywords
Distinct response patterns of endothelial markers to the BNT162b2 mRNA COVID-19 booster vaccine are associated with the spike-specific IgG antibody production
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2024.1471401
Abstract: Introduction Despite the efficacy and safety of SARS-CoV-2 vaccines, inflammatory and/or thrombotic episodes have been reported. Since the impact of COVID-19 vaccines on the endothelium remains uncertain, our objective was to assess endothelial activation status… read more here.
Keywords: endothelial markers; booster; response; mrna covid ... See more keywords