Correlation of Optical and Automated Patch Clamp Electrophysiology for Identification of NaV1.7 Inhibitors
Sign Up to like & getrecommendations! Published in 2020 at "SLAS Discovery"
DOI: 10.1177/2472555220914532
Abstract: The voltage-gated sodium channel Nav1.7 is a genetically validated target for pain; pharmacological blockers are promising as a new class of nonaddictive therapeutics. The search for Nav1.7 subtype selective inhibitors requires a reliable, scalable, and… read more here.
Keywords: spiking hek; hek assay; nav1 inhibitors; optopatch spiking ... See more keywords