Feasibility of coronary endothelial function assessment using arterial spin labeled CMR
Sign Up to like & getrecommendations! Published in 2019 at "NMR in Biomedicine"
DOI: 10.1002/nbm.4183
Abstract: Coronary endothelial dysfunction (CED) is an independent predictor of cardiovascular disease, but its assessment has been limited to invasive coronary angiography. Myocardial perfusion imaging using arterial spin labeled (ASL) cardiac magnetic resonance (CMR) may be… read more here.
Keywords: arterial spin; using arterial; coronary endothelial; assessment ... See more keywords
EPR Techniques to Probe Insertion and Conformation of Spin-Labeled Proteins in Lipid Bilayers.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9512-7_21
Abstract: Electron paramagnetic resonance (EPR) spectroscopy of spin-labeled membrane proteins is a valuable biophysical technique to study structural details and conformational transitions of proteins close to their physiological environment, for example, in liposomes, membrane bilayers, and… read more here.
Keywords: membrane proteins; epr techniques; spin; spectroscopy ... See more keywords
EPR of site-directed spin-labeled proteins: A powerful tool to study structural flexibility.
Sign Up to like & getrecommendations! Published in 2020 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2020.108323
Abstract: Electron Paramagnetic Resonance is a spectroscopic technique which, in combination with site-directed spin-labeling, provides structural and dynamic information about proteins in conditions similar to those of their physiological environment. The information is sequence-resolved as it… read more here.
Keywords: flexibility; epr site; site; site directed ... See more keywords
Alzheimer's Aβ42 and Aβ40 form mixed oligomers with direct molecular interactions.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.11.092
Abstract: Formation of Aβ oligomers and fibrils plays a central role in the pathogenesis of Alzheimer's disease. There are two major forms of Aβ in the brain: Aβ42 and Aβ40. Aβ42 is the major component of… read more here.
Keywords: form mixed; mixed oligomers; form; spin ... See more keywords
High-Resolution Structural Dynamics of Bifunctionally Spin-Labeled Myosin by EPR of Oriented Muscle Fibers
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.11.2394
Abstract: We have performed electron paramagnetic resonance (EPR) on actin-bound myosin labeled with a bifunctional spin label (BSL), in oriented muscle fibers. Our goal was to determine the effect of known small-molecule effectors on the structure… read more here.
Keywords: myosin; actin; spin labeled; epr ... See more keywords
Librational Dynamics of Spin-Labeled Membranes at Cryogenic Temperatures From Echo-Detected ED-EPR Spectra
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.923794
Abstract: Methods of electron spin echo of pulse electron paramagnetic resonance (EPR) spectroscopy are increasingly employed to investigate biophysical properties of nitroxide-labeled biosystems at cryogenic temperatures. Two-pulse echo-detected ED-spectra have proven to be valuable tools to… read more here.
Keywords: echo detected; epr spectra; cryogenic temperatures; spin labeled ... See more keywords
Synthesis of Spin-Labeled Ibuprofen and Its Interaction with Lipid Membranes
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27134127
Abstract: Ibuprofen is a non-steroidal anti-inflammatory drug possessing analgesic and antipyretic activity. Electron paramagnetic resonance (EPR) spectroscopy could be applied to study its interaction with biological membranes and proteins if its spin-labeled analogs were synthesized. Here,… read more here.
Keywords: labeled ibuprofen; spectroscopy; synthesis; spin ... See more keywords