New channel lineup in spinal circuits governing locomotion
Sign Up to like & getrecommendations! Published in 2019 at "Current Opinion in Physiology"
DOI: 10.1016/j.cophys.2018.11.009
Abstract: The locomotor network is a neural circuit capable of generating quite varied and complex patterns of motor activity. While neurotransmission and neuromodulation play a major role in fine-tuning motor function, neuron’s firing properties driven by… read more here.
Keywords: ionic conductances; spinal circuits; new channel; circuits governing ... See more keywords
Voltage imaging identifies spinal circuits that modulate locomotor adaptation in zebrafish
Sign Up to like & getrecommendations! Published in 2022 at "Neuron"
DOI: 10.1016/j.neuron.2022.01.001
Abstract: Motor systems must continuously adapt their output to maintain a desired trajectory. While the spinal circuits underlying rhythmic locomotion are well described, little is known about how the network modulates its output strength. A major… read more here.
Keywords: locomotor adaptation; spinal circuits; voltage imaging;
Voltage imaging and spinal circuits get along swimmingly
Sign Up to like & getrecommendations! Published in 2022 at "Neuron"
DOI: 10.1016/j.neuron.2022.03.024
Abstract: Voltage imaging promises to unite optical and electrical approaches to accelerate circuit discovery. In this issue of Neuron, Böhm et al. (2022) use voltage imaging to explore the structure and functional dynamics of spinal excitatory interneurons… read more here.
Keywords: voltage imaging; spinal circuits; get along; along swimmingly ... See more keywords
Motoneuronal Spinal Circuits in Degenerative Motoneuron Disease
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2020.00074
Abstract: The most evident phenotype of degenerative motoneuron disease is the loss of motor function which accompanies motoneuron death. In both amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA), it is now clear that dysfunction… read more here.
Keywords: motoneuron; motoneuron disease; disease; motoneuronal spinal ... See more keywords