Plasticity of the spinal glymphatic system in male SD rats with painful diabetic neuropathy induced by type 2 diabetes mellitus
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.25104
Abstract: The glymphatic system is a recently discovered glial‐dependent macroscopic interstitial waste clearance system that promotes the efficient elimination of soluble proteins and metabolites from the central nervous system. Its anatomic foundation is the astrocytes and… read more here.
Keywords: system; pdn rats; system male; spinal glymphatic ... See more keywords
Restoration of aquaporin-4 polarization in the spinal glymphatic system by metformin in rats with painful diabetic neuropathy
Sign Up to like & getrecommendations! Published in 2023 at "Neuroreport"
DOI: 10.1097/wnr.0000000000001880
Abstract: Painful diabetic neuropathy (PDN) is a common complication in patients with diabetes, and its underlying mechanism remains unclear. Aquaporin-4 (AQP4) plays a crucial role in removing metabolic waste in the glymphatic system. In this study,… read more here.
Keywords: system; spinal glymphatic; painful diabetic; polarization ... See more keywords
β-Hydroxybutyrate Attenuates Painful Diabetic Neuropathy via Restoration of the Aquaporin-4 Polarity in the Spinal Glymphatic System
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2022.926128
Abstract: Waste removal is essential for maintaining homeostasis and the normal function of the central nervous system (CNS). The glymphatic system based on aquaporin-4 (AQP4) water channels on the endfeet of astrocytes is recently discovered as… read more here.
Keywords: system; diabetic neuropathy; spinal glymphatic; painful diabetic ... See more keywords