Role of C-reactive protein in effective utilization of emergent MRI for spinal infections
Sign Up to like & getrecommendations! Published in 2021 at "Emergency Radiology"
DOI: 10.1007/s10140-020-01892-0
Abstract: Emergent spinal MRI is recommended for patients with back pain and red flags for infection. However, many of these studies are negative due to low prevalence of spinal infections. Our purpose was to assess if… read more here.
Keywords: utilization emergent; spinal infections; mri spinal; emergent mri ... See more keywords
P-93. Contezolid in Patients with Spinal Infections
Sign Up to like & getrecommendations! Published in 2025 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofae631.300
Abstract: Abstract Background Methicillin-resistant Staphylococcus aureus (MRSA) is a common cause of spinal infections (SI) requiring long-term use of antibiotic therapy. Linezolid (LZD) is effective in treating MRSA in different clinical scenarios, but its long-term use… read more here.
Keywords: treatment; oral czd; spinal infections; lzd ... See more keywords
A Combined Scoring Method Based on 18F-FDG PET/CT for Distinguishing Spinal Infection From Malignancy
Sign Up to like & getrecommendations! Published in 2022 at "Spine"
DOI: 10.1097/brs.0000000000004528
Abstract: Study Design. Retrospective study. Objective. This study aimed to explore the additional value of fluorine-18 fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) for the detection of early-stage and atypical spinal infections and to find the… read more here.
Keywords: malignancy; fdg pet; spinal infection; 18f fdg ... See more keywords
The application of endoscopic debridement combined with metagenomic next-generation sequencing technology in primary spinal infections: a retrospective study
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Orthopaedic Surgery and Research"
DOI: 10.1186/s13018-024-05385-5
Abstract: Spinal endoscopy is a novel minimally invasive spinal surgery technique used in recent years to treat various degenerative spinal diseases. Metagenomic next-generation sequencing (mNGS) is a new method for identifying infectious microorganisms in infectious diseases.… read more here.
Keywords: metagenomic next; spinal infections; rate; next generation ... See more keywords
Spinal Infections? mNGS Combined with Microculture and Pathology for Answers
Sign Up to like & getrecommendations! Published in 2024 at "Infection and Drug Resistance"
DOI: 10.2147/idr.s466738
Abstract: Introduction This study evaluates the efficacy of metagenomic next-generation sequencing (mNGS) in diagnosing spinal infections and developing therapeutic regimens that combine mNGS, microbiological cultures, and pathological investigations. Methods Data were collected from 108 patients with… read more here.
Keywords: infections mngs; spinal infections; mngs combined; pathology ... See more keywords
Clinical Features and Treatment Differences Among Tuberculous, Brucellosis, and Pyogenic Spondylitis: A Cohort Study
Sign Up to like & getrecommendations! Published in 2025 at "Infection and Drug Resistance"
DOI: 10.2147/idr.s563720
Abstract: Purpose There was an increasing incidence of spinal infections. This study aimed to compare and contrast the clinical characteristics and treatment regimens for diverse types of spondylitis and to provide guidance for clinicians to make… read more here.
Keywords: treatment; spinal infections; clinical features; pyogenic spondylitis ... See more keywords
Multidisciplinary management of spontaneous spinal infections: is there a correlation between timing, type of treatment and outcome?
Sign Up to like & getrecommendations! Published in 2019 at "Journal of neurosurgical sciences"
DOI: 10.23736/s0390-5616.16.03779-6
Abstract: BACKGROUND Spontaneous spinal infections (SSIs) represent a rare and serious pathological entity. We tried to study a correlation between type of treatment, timing of treatment and clinical outcome through a multivariate analysis of an observational… read more here.
Keywords: treatment; spinal infections; outcome; spontaneous spinal ... See more keywords
Minimally invasive spine surgery in spinal infections.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of neurosurgical sciences"
DOI: 10.23736/s0390-5616.16.03911-4
Abstract: INTRODUCTION Although spinal infections have always been present recently their incidence has increased, in partly fostered by the advances in medicine (i.e. compromised immunity, chronic diseases, increasingly complex spinal procedures, etc.) and increased life expectancy.… read more here.
Keywords: spinal infections; minimally invasive; infections minimally; invasive spine ... See more keywords
Primary spinal infections: A retrospective review of instrumentation use and graft selection
Sign Up to like & getrecommendations! Published in 2022 at "Surgical Neurology International"
DOI: 10.25259/sni_1073_2022
Abstract: Background: The use of instrumentation in the setting of primary spinal infections is controversial. While the instrumentation is often required in the presence of progressive deformity due to spinal osteomyelitis (SO), discitis (SD), or spinal… read more here.
Keywords: without non; infection; spinal infections; instrumentation ... See more keywords
Clinical application value of metagenomic next-generation sequencing in the diagnosis of spinal infections and its impact on clinical outcomes
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2023.1076525
Abstract: This study aimed to evaluate the impact of precise treatment administered according to the results of metagenomic next-generation sequencing (mNGS) on the clinical outcomes of patients with spinal infections. In this multicenter retrospective study, the… read more here.
Keywords: clinical outcomes; patients spinal; group; next generation ... See more keywords
Preliminary research indicates that mechanical force through Pioze1 enhances local immunity during NPWT treatment for spinal infections
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2025.1600194
Abstract: Objective This study aims to investigate the mechanism by which Negative Pressure Wound Therapy (NPWT) regulates local immune responses in spinal infection through Piezo1-mediated mechanical stress, and elucidate its potential role in the treatment of… read more here.
Keywords: treatment spinal; treatment; mechanical force; spinal infections ... See more keywords