Effects of triphenyltin on glycinergic transmission on rat spinal neurons
Sign Up to like & getrecommendations! Published in 2018 at "Environmental Research"
DOI: 10.1016/j.envres.2018.02.005
Abstract: &NA; Glycine is a fast inhibitory transmitter like &ggr;‐aminobutyric acid in the mammalian spinal cord and brainstem, and it is involved in motor reflex, nociception, and neuronal development. Triphenyltin (TPT) is an organometallic compound causing… read more here.
Keywords: spinal neurons; glycinergic transmission; tpt; wild creatures ... See more keywords
Trimetazidine stimulates intracellular Ca2+ transients and zebrafish locomotor activity in spinal neurons
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-06065-y
Abstract: The metabolic modulator trimetazidine (TMZ) is an antianginal recently found to improve skeletal muscle performance in mice models of sarcopenia and of amyotrophic lateral sclerosis (ALS). The mechanism underlying the effect of TMZ on locomotor… read more here.
Keywords: intracellular ca2; spinal neurons; ca2; ca2 transients ... See more keywords
Viral Infections Exacerbate FUS-ALS Phenotypes in iPSC-Derived Spinal Neurons in a Virus Species-Specific Manner
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2019.00480
Abstract: Amyotrophic lateral sclerosis (ALS) arises from an interplay of genetic mutations and environmental factors. ssRNA viruses are possible ALS risk factors, but testing their interaction with mutations such as in FUS, which encodes an RNA-binding… read more here.
Keywords: spinal neurons; als phenotypes; derived spinal; viral infections ... See more keywords