Spinal IL‐33/ST2 signaling mediates chronic itch in mice through the astrocytic JAK2‐STAT3 cascade
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DOI: 10.1002/glia.23639
Abstract: Interleukin‐33 (IL‐33) and its receptor ST2 contribute to spinal glial activation and chronic pain. A recent study showed that peripheral IL‐33 plays a pivotal role in the pathogenesis of chronic itch induced by poison ivy.… read more here.
Keywords: itch; spinal st2; chronic itch; st2 signaling ... See more keywords