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Published in 2021 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2021.174625
Abstract: The present study examined contribution of the transient receptor potential vanilloid 1 channel (TRPV1) to the chronic orofacial pain. Bilateral partial nerve ligation (PNL) of the mental nerve, a branch of trigeminal nerve, was performed…
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Keywords:
pnl rats;
sham rats;
neuropathic pain;
pnl ... See more keywords
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Published in 2019 at "Neuroscience Research"
DOI: 10.1016/j.neures.2018.06.003
Abstract: Although a modulatory role has been reported for α-lipoic acid (LA) on T-type Ca2+ channels in the nervous system, the acute effects of LA in vivo, particularly on nociceptive transmission in the trigeminal system, remain…
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Keywords:
wide dynamic;
administration;
trigeminal nucleus;
dynamic range ... See more keywords
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Published in 2019 at "PAIN"
DOI: 10.1097/j.pain.0000000000001414
Abstract: Abstract Neuropathic pain represents a challenge to clinicians because it is resistant to commonly prescribed analgesics due to its largely unknown mechanisms. Here, we investigated a descending dopaminergic pathway–mediated modulation of trigeminal neuropathic pain. We…
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Keywords:
dopaminergic pathway;
descending dopaminergic;
neuropathic pain;
spinal trigeminal ... See more keywords
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Published in 2020 at "Pain"
DOI: 10.1097/j.pain.0000000000002114
Abstract: The mechanisms underlying headaches attributed to hypoxia are poorly known. The activation of spinal trigeminal neurons with meningeal afferent input is thought to be responsible for the generation of headaches.In the caudal spinal trigeminal nucleus…
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Keywords:
transient activation;
trigeminal neurons;
spinal trigeminal;
activity ... See more keywords
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Published in 2017 at "Journal of Neuroimaging"
DOI: 10.1111/jon.12425
Abstract: Pain information from the face enters the pons via the trigeminal nerve before creating an anatomical “elbow” that turns caudally into the spinal trigeminal tract (SpTV). Visualization of the descending tract of the trigeminal nerve…
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Keywords:
descending tract;
using diffusion;
trigeminal nerve;
nerve ... See more keywords
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Published in 2017 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2017.00336
Abstract: Background/purpose Hydrogen sulfide (H2S) is a neuromodulator acting through nitroxyl (HNO) when it reacts with nitric oxide (NO). HNO activates transient receptor potential channels of the ankyrin type 1 (TRPA1) causing release of calcitonin gene-related…
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Keywords:
model meningeal;
rat model;
hydrogen sulfide;
spinal trigeminal ... See more keywords