Neuregulin 1 (NRG1) fusion‐positive high‐grade spindle cell sarcoma: A distinct group of soft tissue tumors with metastatic potential
Sign Up to like & getrecommendations! Published in 2021 at "Genes"
DOI: 10.1002/gcc.23008
Abstract: Neuregulin 1 (NRG1) is an epidermal growth factor (EGF)‐like ligand that activates receptor tyrosine kinases of the ErbB family of receptors. NRG1 gene fusions, which are rare ( 20/10 high power fields) and tumor necrosis was… read more here.
Keywords: spindle cell; high grade; neuregulin nrg1; spindle ... See more keywords
Naegleria’s mitotic spindles are built from unique tubulins and highlight core spindle features
Sign Up to like & getrecommendations! Published in 2022 at "Current Biology"
DOI: 10.1016/j.cub.2022.01.034
Abstract: Naegleria gruberi is a unicellular eukaryote whose evolutionary distance from animals and fungi has made it useful for developing hypotheses about the last common eukaryotic ancestor. Naegleria amoebae lack a cytoplasmic microtubule cytoskeleton and assemble… read more here.
Keywords: mitotic spindles; spindle; mitotic tubulins; spindles built ... See more keywords
The Xenopus spindle is as dense as the surrounding cytoplasm.
Sign Up to like & getrecommendations! Published in 2021 at "Developmental cell"
DOI: 10.1016/j.devcel.2021.03.013
Abstract: The mitotic spindle is a self-organizing molecular machine, where hundreds of different molecules continuously interact to maintain a dynamic steady state. While our understanding of key molecular players in spindle assembly is significant, it is… read more here.
Keywords: cytoplasm; spindle; dense surrounding; xenopus spindle ... See more keywords
A case report of unilocular cystic mucinous tubular and spindle cell carcinoma with mural tumor nodule
Sign Up to like & getrecommendations! Published in 2019 at "Urology Case Reports"
DOI: 10.1016/j.eucr.2019.101007
Abstract: Mucinous tubular and spindle cell carcinoma (MTSCC) is a rare type of renal cell carcinoma (RCC). Classic type of MTSCC is characterized by small, elongated tubules lined by clear cuboidal or spindle cells with mucinous… read more here.
Keywords: cell carcinoma; spindle; tubular spindle; case ... See more keywords
An experimental investigation on ultra-precision instrumented smart aerostatic bearing spindle applied to high speed micro-drilling
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Manufacturing Processes"
DOI: 10.1016/j.jmapro.2017.11.022
Abstract: Abstract High speed drilling of small diameter holes ranging from 0.1 to 1 mm in printed circuit board (PCB) drilling industry has been largely carried out by using tungsten carbide twist drills and high speed spindles.… read more here.
Keywords: spindle; drilling; displacement; instrumented smart ... See more keywords
SPINDLE CELL VARIANT OF RHABDOMYOSARCOMA IN THE ORAL CAVITY: A CASE REPORT
Sign Up to like & getrecommendations! Published in 2021 at "Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology"
DOI: 10.1016/j.oooo.2021.03.181
Abstract: Introduction Rhabdomyosarcoma (RMS) is a malignant mesenchymal tumor derived from skeletal muscle. The head and neck, genitourinary tract, and extremities are the most common sites for RMS. RMS is less frequent in the oral cavity,… read more here.
Keywords: spindle cell; report; case; cell variant ... See more keywords
Aurora-A promotes the establishment of spindle assembly checkpoint by priming the Haspin-Aurora-B feedback loop in late G2 phase
Sign Up to like & getrecommendations! Published in 2017 at "Cell Discovery"
DOI: 10.1038/celldisc.2016.49
Abstract: Aurora-A kinase functions mainly in centrosome maturation, separation and spindle formation. It has also been found to be amplified or overexpressed in a range of solid tumors, which is linked with tumor progression and poor… read more here.
Keywords: spindle; checkpoint; haspin; late phase ... See more keywords
MYOD1-mutant spindle cell and sclerosing rhabdomyosarcoma: an aggressive subtype irrespective of age. A reappraisal for molecular classification and risk stratification
Sign Up to like & getrecommendations! Published in 2018 at "Modern Pathology"
DOI: 10.1038/s41379-018-0120-9
Abstract: Sclerosing and spindle cell rhabdomyosarcoma is a rare histologic subtype, designated in the latest WHO classification as a stand-alone pathologic entity. Three genomic groups have been defined: an infantile subset of spindle cell rhabdomyosarcoma harboring… read more here.
Keywords: spindle; spindle cell; rhabdomyosarcoma; sclerosing rhabdomyosarcoma ... See more keywords
Infantile Fibrosarcoma and Other Spindle Cell Neoplasms of Infancy. A Review of Morphologically Overlapping yet Molecularly Distinctive Entities
Sign Up to like & getrecommendations! Published in 2022 at "Fetal and Pediatric Pathology"
DOI: 10.1080/15513815.2021.2024631
Abstract: Abstract Background Regardless of age at presentation, many soft tissue neoplasms have overlapping histopathologic and immunophenotypic features to serve as a diagnostic challenge. Case report We reported a case of a spindle cell neoplasm in… read more here.
Keywords: spindle cell; spindle; cell neoplasms; fibrosarcoma spindle ... See more keywords
O-171 Altered meiotic spindle morphology and composition in in vitro matured oocytes
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DOI: 10.1093/humrep/deab127.052
Abstract: How does the meiotic spindle tubulin PTMs of MII oocytes matured in vitro compare to that of MII oocytes matured in vivo? MII cultured in vitro present detyrosinated tubulin in the spindle microtubules, while MII… read more here.
Keywords: vivo matured; mii; spindle; mii oocytes ... See more keywords
Spontaneous slow oscillation—slow spindle features predict induced overnight memory retention
Sign Up to like & getrecommendations! Published in 2021 at "Sleep"
DOI: 10.1093/sleep/zsab127
Abstract: Abstract Study Objectives Synchronization of neural activity within local networks and between brain regions is a major contributor to rhythmic field potentials such as the EEG. On the other hand, dynamic changes in microstructure and… read more here.
Keywords: baseline sleep; stimulation; spindle; retention ... See more keywords