Efficacy of endoscopic‐guided fine‐needle aspiration in the diagnosis of gastrointestinal spindle cell tumors
Sign Up to like & getrecommendations! Published in 2018 at "Diagnostic Cytopathology"
DOI: 10.1002/dc.23976
Abstract: Spindle cell neoplasms of the gastrointestinal (GI) tract constitute a wide group of lesions that may raise diagnostic difficulties on hematoxylin–eosin‐stained slides. Appropriate endoscopic ultrasound‐guided fine‐needle aspiration (EUS‐FNA) technique with sufficient cell block material for… read more here.
Keywords: guided fine; needle aspiration; spindle cell; fine needle ... See more keywords
Spindle cell neoplasms of the upper gastrointestinal tract, hepatobiliary tract, and pancreas by fine needle aspiration: A single institutional experience of 15 years with follow‐up data
Sign Up to like & getrecommendations! Published in 2021 at "Diagnostic Cytopathology"
DOI: 10.1002/dc.24801
Abstract: The diagnosis of spindle cell neoplasms (SCN) of the upper gastrointestinal (GI) tract, hepatobiliary tract, and pancreas detected by fine needle aspiration (FNA) is challenging. We describe a single‐center experience of these samples with follow‐up… read more here.
Keywords: gastrointestinal tract; cell neoplasms; upper gastrointestinal; tract hepatobiliary ... See more keywords
Spindle cell lesion on fine needle aspiration as an initial step for diagnosis of lymphangioleiomyomatosis: Report of a rare case
Sign Up to like & getrecommendations! Published in 2021 at "Diagnostic Cytopathology"
DOI: 10.1002/dc.24802
Abstract: Lymphangioleiomyomatosis (LAM) is a rare systemic disease of women of reproductive age characterized by proliferation of abnormal smooth muscle like cells (LAM cells). Patients with LAM characteristically present with chronic dyspnea and cough and less… read more here.
Keywords: diagnosis; needle aspiration; case; fine needle ... See more keywords
Can EUS‐FNA cytology reliably classify gastric submucosal spindle cell tumors?
Sign Up to like & getrecommendations! Published in 2023 at "Diagnostic Cytopathology"
DOI: 10.1002/dc.25097
Abstract: Cytological diagnosis using endoscopic ultrasound‐guided fine‐needle aspiration (EUS‐FNA) for gastric submucosal spindle cell tumors, such as gastrointestinal stromal tumors (GISTs), leiomyomas, and schwannomas, is challenging because of their similar morphological characteristics. read more here.
Keywords: gastric submucosal; eus fna; spindle cell; submucosal spindle ... See more keywords
S100 and CD34 positive spindle cell tumor with prominent perivascular hyalinization and a novel NCOA4‐RET fusion
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DOI: 10.1002/gcc.22758
Abstract: We report a case of a 35‐year old male patient with a tumor located in the deep dermis on his forearm. The lesion was completely excised but recurred 4 years later. The patient showed no signs… read more here.
Keywords: perivascular hyalinization; spindle cell; s100 cd34; fusion ... See more keywords
Neuregulin 1 (NRG1) fusion‐positive high‐grade spindle cell sarcoma: A distinct group of soft tissue tumors with metastatic potential
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DOI: 10.1002/gcc.23008
Abstract: Neuregulin 1 (NRG1) is an epidermal growth factor (EGF)‐like ligand that activates receptor tyrosine kinases of the ErbB family of receptors. NRG1 gene fusions, which are rare ( 20/10 high power fields) and tumor necrosis was… read more here.
Keywords: spindle cell; high grade; neuregulin nrg1; spindle ... See more keywords
Tyrosine kinase‐altered spindle cell neoplasms with EGFR internal tandem duplications
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DOI: 10.1002/gcc.23067
Abstract: In this study, we present two extra‐renal pediatric spindle cell neoplasms with epidermal growth factor receptor (EGFR) internal tandem duplications (ITD). Histologically, these tumors demonstrated the same histologic features seen in other tyrosine kinase‐altered spindle… read more here.
Keywords: altered spindle; kinase altered; spindle cell; cell neoplasms ... See more keywords
Recurrent VGLL3 fusions define a distinctive subset of spindle cell rhabdomyosarcoma with an indolent clinical course and striking predilection for the head and neck
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DOI: 10.1002/gcc.23083
Abstract: The mammalian Vestigial‐like (VGLL) transcriptional cofactor family of proteins VGLL1‐4 has recently emerged as an important player in the tumorigenesis of diverse neoplasms. The role of VGLL3 in soft tissue tumors is exemplified by its… read more here.
Keywords: vgll3 fusions; spindle cell; predilection head; head neck ... See more keywords
EGFR internal tandem duplications in fusion‐negative congenital and neonatal spindle cell tumors
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DOI: 10.1002/gcc.23087
Abstract: Next‐generation sequencing (NGS) assays can sensitively detect somatic variation, and increasingly can enable the identification of complex structural rearrangements. A subset of infantile spindle cell sarcomas, particularly congenital mesoblastic nephromas with classic or mixed histology,… read more here.
Keywords: spindle cell; egfr itd; histology; internal tandem ... See more keywords
Complete mimicry: Rhabdomyosarcoma with FUS::TFCP2 fusion masquerading as carcinoma—diagnostic challenge and report of two cases
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DOI: 10.1002/gcc.23145
Abstract: Rhabdomyosarcomas (RMS) are malignant mesenchymal tumors with skeletal muscle differentiation which are classified into alveolar, embryonal, pleomorphic, and spindle cell/sclerosing RMS. Within the spindle cell/sclerosing RMS tumor type there is a recently recognized sub‐type categorized… read more here.
Keywords: cell; fusion; fus tfcp2; report two ... See more keywords
Growth of doxorubicin‐resistant undifferentiated spindle‐cell sarcoma PDOX is arrested by metabolic targeting with recombinant methioninase
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DOI: 10.1002/jcb.26527
Abstract: Undifferentiated spindle‐cell sarcoma (USCS) is a recalcitrant cancer in need of individualized therapy. A high‐grade USCS from a striated muscle of a patient was grown orthotopically in the right biceps femoris muscle of nude mice… read more here.
Keywords: recombinant methioninase; spindle cell; cell sarcoma; pdox ... See more keywords