Spindle Dynamics Model Explains Chromosome Loss Rates in Yeast Polyploid Cells
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2018.00296
Abstract: Faithful chromosome segregation, driven by the mitotic spindle, is essential for organismal survival. Neopolyploid cells from diverse species exhibit a significant increase in mitotic errors relative to their diploid progenitors, resulting in chromosome nondisjunction. In… read more here.
Keywords: chromosome loss; dynamics model; spindle dynamics; model ... See more keywords