Rnd3 interacts with TAO kinases and contributes to mitotic cell rounding and spindle positioning
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DOI: 10.1242/jcs.235895
Abstract: ABSTRACT Rnd3 is an atypical Rho family protein that is constitutively GTP bound, and acts on membranes to induce loss of actin stress fibers and cell rounding. Phosphorylation of Rnd3 promotes 14-3-3 binding and its… read more here.
Keywords: mitotic cell; rounding spindle; spindle positioning; cell rounding ... See more keywords
Three-dimensional geometry controls division symmetry in stem cell colonies.
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DOI: 10.1242/jcs.255018
Abstract: Proper control of division orientation and symmetry, largely determined by spindle positioning, is essential to development and homeostasis. Spindle positioning has been extensively studied in cells dividing in 2-dimensional (2D) environments and in epithelial tissues,… read more here.
Keywords: division; spindle positioning; geometry; symmetry ... See more keywords
FAM83D directs protein kinase CK1α to the mitotic spindle for proper spindle positioning
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DOI: 10.15252/embr.201847495
Abstract: The concerted action of many protein kinases helps orchestrate the error‐free progression through mitosis of mammalian cells. The roles and regulation of some prominent mitotic kinases, such as cyclin‐dependent kinases, are well established. However, these… read more here.
Keywords: ck1; spindle positioning; proper spindle; fam83d directs ... See more keywords