Articles with "spines calcineurin" as a keyword



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Alzheimer's Disease, Dendritic Spines, and Calcineurin Inhibitors: A New Approach?

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Published in 2018 at "ACS chemical neuroscience"

DOI: 10.1021/acschemneuro.8b00213

Abstract: Therapeutics to effectively treat Alzheimer's disease (AD) are lacking. In vitro, animal and human studies have implicated the excessive activation of the protein phosphatase calcineurin (CN) as an early step in the pathogenesis of AD.… read more here.

Keywords: calcineurin inhibitors; disease dendritic; alzheimer disease; dendritic spines ... See more keywords