Serine peptidase inhibitor Kazal type III (SPINK3) promotes BRL‐3A cell proliferation by targeting the PI3K–AKT signaling pathway
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29130
Abstract: The serine protease inhibitor, Kazal type III (SPINK3), is a trypsin inhibitor associated with liver disease, which highly overexpresses in a variety of cancers. In one of our previous studies of our laboratory, Spink3 was… read more here.
Keywords: spink3; cell proliferation; pi3k akt; proliferation ... See more keywords
Recombinant SPINK3 improves ram sperm quality and in vitro fertility after cryopreservation.
Sign Up to like & getrecommendations! Published in 2019 at "Theriogenology"
DOI: 10.1016/j.theriogenology.2019.12.019
Abstract: Capacitation-like changes affect sperm of several species, such as ram, reducing cell survival and fertilizing competence. Proteins from seminal plasma stabilize sperm plasma membranes, being an interesting focus to develop strategies for improving cryopreserved ram… read more here.
Keywords: quality; spink3; cryopreservation; ram sperm ... See more keywords
How, where and when is SPINK3 bound and removed from mouse sperm?
Sign Up to like & getrecommendations! Published in 2022 at "Reproduction"
DOI: 10.1530/rep-21-0195
Abstract: Sperm capacitation in mammals is a fundamental requirement to acquire their fertilizing capacity. Little is known about the action mechanism of the molecules that prevent capacitation from occurring prematurely. These molecules are known as decapacitation… read more here.
Keywords: capacitation; removed mouse; spink3; bound removed ... See more keywords