On the ground and in the heights: Does exploratory activity differ in commensal and non-commensal spiny mice?
Sign Up to like & getrecommendations! Published in 2020 at "Behavioural Processes"
DOI: 10.1016/j.beproc.2020.104252
Abstract: Human settlements represent a specific environment where commensal animals are exposed to different selective pressures than their wild-living conspecifics. Despite the importance of commensal rodents for human health and economy, little is known about how… read more here.
Keywords: non commensal; ground; commensal; commensal non ... See more keywords
Adaptations in Hippo-Yap signaling and myofibroblast fate underlie scar-free ear appendage wound healing in spiny mice.
Sign Up to like & getrecommendations! Published in 2021 at "Developmental cell"
DOI: 10.1016/j.devcel.2021.09.008
Abstract: Spiny mice (Acomys cahirinus) are terrestrial mammals that evolved unique scar-free regenerative wound-healing properties. Myofibroblasts (MFs) are the major scar-forming cell type in skin. We found that following traumatic injury to ear pinnae, MFs appeared… read more here.
Keywords: wound healing; scar free; fate; spiny mice ... See more keywords
Postpartum ovulation and early pregnancy in the menstruating spiny mouse, Acomys cahirinus
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-84361-z
Abstract: Egyptian spiny mice are the only known species to have human-like menstruation and a postpartum ovulation. Unfortunately, no endocrine or morphological evidence has been provided for a postpartum ovulation in spiny mice, and while later… read more here.
Keywords: pregnancy; postpartum ovulation; ovulation; spiny mice ... See more keywords
An ERK-dependent molecular switch antagonizes fibrosis and promotes regeneration in spiny mice (Acomys)
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.adf2331
Abstract: Although most mammals heal wounds with scar tissue, spiny mice (Acomys cahirinus) naturally regenerate skin and complex musculoskeletal tissues. The core signaling pathways driving mammalian tissue regeneration are poorly characterized. Here, we show that MAPK/ERK… read more here.
Keywords: regeneration; fibrosis; mice acomys; spiny mice ... See more keywords
Spiny mice (Acomys) exhibit attenuated hallmarks of aging and rapid cell turnover after UV exposure in the skin epidermis
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0241617
Abstract: The study of long-lived and regenerative animal models has revealed diverse protective responses to stressors such as aging and tissue injury. Spiny mice (Acomys) are a unique mammalian model of skin wound regeneration, but their… read more here.
Keywords: mice acomys; skin; skin epidermis; mice ... See more keywords
Spiny mice (Acomys) cells fail to engraft in NOD scid gamma
Sign Up to like & getrecommendations! Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0286000
Abstract: Immune cells and stromal cells regulate wound healing and regeneration through complex activation patterns with spatiotemporal variation. The scarless regeneration of Spiny mice (Acomys species) is no exception; differential activation of immune and stromal cell… read more here.
Keywords: nod scid; acomys cells; spiny mice; scid gamma ... See more keywords