Isatins 3-C annulation vs ring-opening: Two different pathways for synthesis of spiro compounds via multicomponent reactions
Sign Up to like & getrecommendations! Published in 2019 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2019.151181
Abstract: Abstract An efficient synthesis of spiro compounds via two different pathways from the reactions of isatins, 3-phenylisoxazol-5(4H)-one (3-ethylisoxazol-5(4H)-one), and pyrazol-5-amine (6-aminopyrimidine-2,4(1H,3H)-dione) were reported. The catalyst Amberlyst-15 could be easy recycled and reused for many time… read more here.
Keywords: different pathways; spiro; spiro compounds; compounds via ... See more keywords
Spiro Derivatives in the Discovery of New Pesticides: A Research Review.
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DOI: 10.1021/acs.jafc.2c02301
Abstract: Spiro compounds are biologically active organic compounds with unique structures, found in a wide variety of natural products and drugs. They do not readily lead to drug resistance due to their unique mechanisms of action… read more here.
Keywords: new pesticides; spiro compounds; derivatives discovery; discovery new ... See more keywords
Orthogonal Boron-Nitrogen Spiro Compounds: Donor-Acceptor Strength Modulation for Thermally Activated Delayed Fluorescence Emitters with Aggregation induced Emission Enhancement
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DOI: 10.1039/d5tc00793c
Abstract: A series of boron-nitrogen spiro compounds were synthesized using the "intermolecular locking" strategy, and the effects on the properties of the compounds by changing the strength of the donor (D)... read more here.
Keywords: nitrogen spiro; spiro compounds; boron nitrogen;
Facile synthesis of hydantoin/1,2,4-oxadiazoline spiro-compounds via 1,3-dipolar cycloaddition of nitrile oxides to 5-iminohydantoins
Sign Up to like & getrecommendations! Published in 2025 at "Beilstein Journal of Organic Chemistry"
DOI: 10.3762/bjoc.21.118
Abstract: The cycloaddition of 1,3-dipoles at C=N bonds is a relatively rare process, in contrast to the widespread cycloaddition reactions at C=C, C≡C, and C=S bonds. In this study, we present the syntheses of novel hydantoin/1,2,4-oxadiazoline… read more here.
Keywords: dipolar cycloaddition; oxadiazoline spiro; cycloaddition nitrile; hydantoin oxadiazoline ... See more keywords