Spiro Derivatives in the Discovery of New Pesticides: A Research Review.
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DOI: 10.1021/acs.jafc.2c02301
Abstract: Spiro compounds are biologically active organic compounds with unique structures, found in a wide variety of natural products and drugs. They do not readily lead to drug resistance due to their unique mechanisms of action… read more here.
Keywords: new pesticides; spiro compounds; derivatives discovery; discovery new ... See more keywords
Design, Synthesis, and Bioactivity of Spiro Derivatives Containing a Pyridine Moiety.
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DOI: 10.1021/acs.jafc.2c06189
Abstract: We designed and synthesized a series of pyridine spiro derivatives and evaluated their insecticidal and antiviral activities. Some compounds exhibited good insecticidal and antiviral activities. Notably, the E series of compounds displayed good insecticidal activity… read more here.
Keywords: compounds e20; design synthesis; bioactivity spiro; spiro derivatives ... See more keywords
Prediction of the Synthesis of Spiro Derivatives by Double Intramolecular Aromatic Electrophilic Substitution Using Reactivity Indices
Sign Up to like & getrecommendations! Published in 2019 at "ACS Omega"
DOI: 10.1021/acsomega.8b03368
Abstract: The synthesis of heterocyclic spirobifluorene (SBF) analogs generally requires long and complicated synthetic pathways. Despite this synthetic effort, such structural modification allows the (opto)electronic properties of this remarkable three-dimensional node to be tuned especially for… read more here.
Keywords: synthesis; synthesis spiro; spiro derivatives; aromatic electrophilic ... See more keywords