Regioselective Synthesis of Spiro-Ganoderma Meroterpenoid Motifs via Lewis Acid-Catalyzed Divergent Cycloadditions: [3 + 2] and Water Accelerated [5 + 2] Annulations.
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DOI: 10.1021/acs.orglett.5c03622
Abstract: For the first time, a water-driven Lewis acid-catalyzed [5 + 2] cyclization between allylsilanes and aurones was developed, affording spiro-Ganoderma-meroterpenoid (SGM) motifs with high yields and stereoselectivity. This method enables efficient construction of spiro-tricyclic rings,… read more here.
Keywords: spiro ganoderma; spiro; ganoderma meroterpenoid; water ... See more keywords
Total synthesis of spiro Ganoderma meroterpenoids spiroapplanatumines B, D, F, and H
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DOI: 10.1039/d4qo01147c
Abstract: The first total synthesis of spiroapplanatumines B (2), D (4), F (6), and H (8) as well as the possibly undiscovered natural product spiroapplanatumine R (10) have been realized in... read more here.
Keywords: spiro ganoderma; total synthesis; ganoderma meroterpenoids; synthesis ... See more keywords