Synthesis of spiro[indolizidine-1,3′-oxindole] from l-glutamic acid
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DOI: 10.1016/j.tet.2020.131261
Abstract: Abstract Spiro[indolizidine-1,3′-oxindole] compounds have been synthesized in enantiomerically pure form from l -glutamic acid. The key oxidative ring contraction of chiral indolo[2,3-a]quinolizidinone was achieved by treatment with N-bromosuccinimide in tetrahydrofuran/water in the presence of catalytic… read more here.
Keywords: indolizidine oxindole; glutamic acid; spiro indolizidine; acid ... See more keywords