Design, synthesis, docking studies and biological evaluation of novel dihydro-1,3,5-triazines as human DHFR inhibitors.
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DOI: 10.1016/j.ejmech.2016.11.010
Abstract: A novel series of dihydro-1,3,5-triazine derivatives bearing a heteroatom spiro-ring were designed and synthesized on the basis of molecular flexible docking work, and their biological activities were evaluated. Compounds A2, A5, B1 and B3 showed… read more here.
Keywords: novel; design synthesis; dihydro; synthesis docking ... See more keywords
Study of Random Walk Invariants for Spiro-Ring Network Based on Laplacian Matrices
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DOI: 10.3390/math12091309
Abstract: The use of the global mean first-passage time (GMFPT) in random walks on networks has been widely explored in the field of statistical physics, both in theory and practical applications. The GMFPT is the estimated… read more here.
Keywords: spiro ring; study random; network; ring networks ... See more keywords