Carbene-catalyzed enantioselective construction of a quasi-symmetrical spirocyclic hydroquinone with a minor chiral distinction
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DOI: 10.1039/d5sc01605c
Abstract: Constructing a nearly symmetrical chiral center with tiny chiral differences is a challenging task in asymmetric synthesis. The natural antibiotic fredericamycin A (FDM-A), a representative example, has a unique structure with a quasi-symmetrical spirocyclic hydroquinone… read more here.
Keywords: catalyzed enantioselective; spirocyclic hydroquinone; hydroquinone; symmetrical spirocyclic ... See more keywords