A three-component, general and practical route for diastereoselective synthesis of aza-spirocyclic pyrazolones via a decarboxylative annulation process
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DOI: 10.1039/d0nj05915c
Abstract: An efficient, general, and practical route for highly diastereoselective synthesis of aza-spirocyclic pyrazolones from easily available α-amino acids, aldehydes, and alkylidene pyrazolones by means of a decarboxylative annulation process is reported. This high-yielding reaction proceeds… read more here.
Keywords: diastereoselective synthesis; spirocyclic pyrazolones; general practical; aza spirocyclic ... See more keywords