An Efficient Method for Synthesis of Some Novel Spirooxindole-4H-Pyran Derivatives
Sign Up to like & getrecommendations! Published in 2019 at "Polycyclic Aromatic Compounds"
DOI: 10.1080/10406638.2019.1686405
Abstract: Abstract Oxindoles and spirooxindoles as poly-functionalized heterocycles are important synthetic targets because of their biological activity and applications to pharmaceutical guide discovery. The spirooxindole structure is usually found in a variety of complex alkaloids and… read more here.
Keywords: spirooxindole pyran; synthesis novel; efficient method; spirooxindole ... See more keywords
Discovery of a cytochrome P450 enzyme catalyzing the formation of spirooxindole alkaloid scaffold
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2023.1125158
Abstract: Spirooxindole alkaloids feature a unique scaffold of an oxindole ring sharing an atom with a heterocyclic moiety. These compounds display an extensive range of biological activities such as anticancer, antibiotics, and anti-hypertension. Despite their structural… read more here.
Keywords: cytochrome p450; spirooxindole; p450 enzyme;