Stereoselective Synthesis of Spirooxindole Derivatives Using One-Pot Multicomponent Cycloaddition Reaction and Evaluation of Their Antiproliferative Efficacy
Sign Up to like & getrecommendations! Published in 2020 at "ACS Omega"
DOI: 10.1021/acsomega.0c03675
Abstract: A highly stereoselective, one-pot, multicomponent method has been developed to synthesize pyrrolizidine- and N-methyl pyrrolidine-substituted spirooxindole derivatives. The [3 + 2] cycloaddition reaction involves the reaction between the dipole azomethine ylides, generated in situ from… read more here.
Keywords: pot multicomponent; antiproliferative efficacy; reaction; one pot ... See more keywords
Novel cellulose supported 1,2-bis(4-aminophenylthio)ethane Ni(ii) complex (NiII(BAPTE)(NO3)2-Cell) as an efficient nanocatalyst for the synthesis of spirooxindole derivatives
Sign Up to like & getrecommendations! Published in 2022 at "RSC Advances"
DOI: 10.1039/d1ra08182a
Abstract: Cellulose was used as a support for immobilizing a Ni(ii) complex of 1,2-bis(4-aminophenylthio)ethane to prepare NiII(BAPTE)(NO3)2-Cell as a new organo–inorganic hybrid nanocatalyst. The properties of the prepared catalyst were studied using various analyses such as… read more here.
Keywords: spirooxindole derivatives; bis aminophenylthio; bapte no3; no3 cell ... See more keywords
Ammonium acetate mediated simple, rapid, and one-pot multicomponent synthesis of spirooxindole derivatives
Sign Up to like & getrecommendations! Published in 2023 at "Synthetic Communications"
DOI: 10.1080/00397911.2023.2199357
Abstract: Abstract Synthesis of spirooxindole derivatives was achieved by combining Knoevenagel condensation and Michael addition between isatin, malononitrile, and dimedone or cyclohexan-1,3-dione in presence of ammonium acetate by simple stirring in ethanol at room temperature. Spirooxindole… read more here.
Keywords: acetate mediated; synthesis spirooxindole; mediated simple; ammonium acetate ... See more keywords