Immobilization of trypsin onto polyamidoamine dendrimer functionalized iron oxide nanoparticles and its catalytic behavior towards spirooxindole-pyran derivatives in aqueous media
Sign Up to like & getrecommendations! Published in 2020 at "Materials today communications"
DOI: 10.1016/j.mtcomm.2020.101759
Abstract: Abstract A novel biocatalyst of trypsin (Fe3O4@SiO2@D-NHCS-Tr) was prepared based on PAMAM dendrimer immobilized on the surface of magnetic nanoparticles. Then, the catalyst performance was evaluated by the green synthesis of spirooxindole-pyran derivatives for the… read more here.
Keywords: spirooxindole pyran; dendrimer; immobilization trypsin; pyran derivatives ... See more keywords
Dynamic stereoselective annulation via aldol-oxa-cyclization cascade reaction to afford spirooxindole pyran polycycles
Sign Up to like & getrecommendations! Published in 2019 at "Communications Chemistry"
DOI: 10.1038/s42004-019-0177-5
Abstract: Spiro polycyclic compounds bearing pyran ring systems are found in bioactive molecules, and we recently reported the construction of spirooxindole all-carbon polycycles. Here we show the development of catalytic stereoselective annulation reactions that afford spirooxindole… read more here.
Keywords: spirooxindole pyran; carbon; aldol oxa; pyran ... See more keywords
An Efficient Method for Synthesis of Some Novel Spirooxindole-4H-Pyran Derivatives
Sign Up to like & getrecommendations! Published in 2019 at "Polycyclic Aromatic Compounds"
DOI: 10.1080/10406638.2019.1686405
Abstract: Abstract Oxindoles and spirooxindoles as poly-functionalized heterocycles are important synthetic targets because of their biological activity and applications to pharmaceutical guide discovery. The spirooxindole structure is usually found in a variety of complex alkaloids and… read more here.
Keywords: spirooxindole pyran; synthesis novel; efficient method; spirooxindole ... See more keywords