Articles with "spirooxindoles incorporating" as a keyword



Intramolecular H-Bonds in an Organocatalyst Enabled an Asymmetric Michael/Alkylation Cascade Reaction to Construct Spirooxindoles Incorporating a Densely Substituted Cyclopropane Motif.

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Published in 2022 at "Organic letters"

DOI: 10.1021/acs.orglett.2c03578

Abstract: A cascade Michael addition/alkylation reaction between 3-chlorooxindoles and α-cyano chalcones catalyzed using a multifunctional quinine-derived aminoindanol-thiourea substance was investigated. A series of spirooxindoles incorporating a densely substituted cyclopropane motif were efficiently obtained with moderate to… read more here.

Keywords: cyclopropane motif; densely substituted; spirooxindoles incorporating; incorporating densely ... See more keywords