Synthesis of spiropyrrolidine oxindoles via Ag-catalyzed stereo- and regioselective 1,3-dipolar cycloaddition of indole-based azomethine ylides with chalcones
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DOI: 10.1039/c8nj04492a
Abstract: The synthesis of novel spiropyrrolidine oxindole derivatives was reported, using Ag-catalyzed [3+2] cycloaddition of azomethine ylides generated in situ from the condensation of substituted isatins and primary α-amino acid esters with chalcones. Products bearing four… read more here.
Keywords: cycloaddition; azomethine ylides; synthesis spiropyrrolidine; spiropyrrolidine oxindoles ... See more keywords