ALK‐positive compound Spitz nevus with extensive perineural and intraneural neurotropism
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cutaneous Pathology"
DOI: 10.1111/cup.13890
Abstract: Historically recognized by their characteristic histopathologic features, Spitz neoplasms are now known to be molecularly defined by mutually exclusive recurrent abnormalities that cause activation of the MAPK pathway. Spitz neoplasms with ALK rearrangements frequently demonstrate… read more here.
Keywords: neurotropism; compound spitz; alk positive; spitz ... See more keywords
Malignant melanoma test results by a commercial 35‐gene expression test are enriched for benign or atypical Spitz tumors
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cutaneous Pathology"
DOI: 10.1111/cup.14312
Abstract: 200, respectively), diagnosed as an epithelioid Spitz nevus, arose on the forearm of a 54-year-old man and showed a superficial plaque like, predominantly intradermal proliferation of enlarged spitzoid melanocytes arrayed in small nests, cords, and… read more here.
Keywords: spitz; test; test results; results commercial ... See more keywords
Spitz melanocytic tumours – a review
Sign Up to like & getrecommendations! Published in 2022 at "Histopathology"
DOI: 10.1111/his.14583
Abstract: Spitz tumours comprise a spectrum of melanocytic proliferations that share a set of distinct cytological features and molecular pathways. They include benign naevi, intermediate or indeterminate tumours and rare melanomas. Spitz tumours are notorious for… read more here.
Keywords: genomic aberrations; tumours review; melanocytic tumours; spitz ... See more keywords
The Spectrum of Spitz Melanocytic Lesions: From Morphologic Diagnosis to Molecular Classification
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.889223
Abstract: Spitz tumors represent a distinct subtype of melanocytic lesions with characteristic histopathologic features, some of which are overlapping with melanoma. More common in the pediatric and younger population, they can be clinically suspected by recognizing… read more here.
Keywords: lesions morphologic; melanocytic lesions; spitz; spitz melanocytic ... See more keywords