Tuftsin ameliorates splenic inflammatory injury by promoting neuropilin-1 in severe acute pancreatitis.
Sign Up to like & getrecommendations! Published in 2022 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2022.115030
Abstract: Severe acute pancreatitis (SAP)-associated spleen injury causing immune disturbances aggravates organs injuries, which contributes to higher mortality rate. However, there are no effective drugs to cure SAP-induced spleen injury. Here, we found that Tuftsin (TN)… read more here.
Keywords: acute pancreatitis; sap; injury promoting; injury ... See more keywords
Hyperoside Attenuates Zearalenone-induced spleen injury by suppressing oxidative stress and inhibiting apoptosis in mice.
Sign Up to like & getrecommendations! Published in 2021 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2021.108408
Abstract: Zearalenone (ZEA) is a ubiquitous mycotoxin contaminant that causes immune toxicity, apoptosis, and oxidative stress in animals. Hyperoside (Hyp) is a flavonol glycoside compound with antioxidant and anti-apoptotic properties. However, the potential of Hyp to… read more here.
Keywords: induced spleen; spleen injury; oxidative stress; zea induced ... See more keywords
The benefits of limiting scheduled blood draws in children with a blunt liver or spleen injury.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of pediatric surgery"
DOI: 10.1016/j.jpedsurg.2019.05.006
Abstract: BACKGROUND Nonoperative management protocols of blunt liver and spleen injury in children usually call for serial monitoring of the child's hemoglobin and hematocrit (H/H) at scheduled intervals. We previously demonstrated that the need for emergent… read more here.
Keywords: blood draws; spleen injury; liver spleen; injury ... See more keywords
Changes to the myocardial enzyme spectrum in patients with different degrees of spleen injury and their clinical value
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DOI: 10.1097/md.0000000000031028
Abstract: To investigate the changes to the myocardial enzyme profile and its clinical value in patients with different degrees of spleen injury. Of all patients who underwent total splenectomy due to trauma-induced spleen injury from January… read more here.
Keywords: group; spleen injury; myocardial enzyme; control group ... See more keywords
Beneficial Effect of Rosuvastatin Therapy on Spleen Injury Induced by Gamma Irradiation in Rats: Targeting Nrf2/EPRE Pathway
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DOI: 10.1177/15593258231179900
Abstract: Purpose The present study investigates the new approach of rosuvastatin (RUV) administration as a drug for the management of spleen injury induced by gamma irradiation. Main Methods Forty rats were used and divided equally into… read more here.
Keywords: spleen injury; gamma irradiation; injury induced; rosuvastatin ... See more keywords
Comparison of Long-Term Pneumonia Risk between Spleen Injury and Non-Spleen Injury after Total Splenectomy—A Population-Based Study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm12020308
Abstract: Patients who undergo splenectomy are at a high risk of infection. We aimed to investigate the rate of pneumonia in patients who underwent splenectomy, specifically comparing those who had splenectomy due to spleen injury and… read more here.
Keywords: pneumonia risk; injury; spleen injury; population based ... See more keywords