Subtotal versus total splenectomy in children with sickle cell disease: Clinical outcomes and splenic function assessed by pocked red blood cell count
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DOI: 10.1182/blood-2025-2953
Abstract: Background: The spleen is one of the first organs affected by sickle cell disease (SCD). While splenectomy may be indicated in some patients to prevent life-threatening recurrent acute splenic sequestration (ASS), the choice between subtotal… read more here.
Keywords: splenectomy; total splenectomy; splenic function; subtotal splenectomy ... See more keywords
Alterations in splenic function and gene expression in mice with depressive-like behavior induced by exposure to corticosterone
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DOI: 10.3892/ijmm.2017.2850
Abstract: Depressed patients present with increased cortisol levels and attenuated immune responses. However, little is known about the association between depression and the spleen, as this is the largest peripheral immune organ. In this study, we… read more here.
Keywords: splenic function; mice depressive; like behavior; depressive like ... See more keywords