Splenic marginal zone lymphoma: A US population‐based survival analysis (1999‐2016)
Sign Up to like & getrecommendations! Published in 2020 at "Cancer"
DOI: 10.1002/cncr.33117
Abstract: Splenic marginal zone lymphoma (SMZL) is a rare tumor without a uniform treatment approach. The authors describe a large population‐based study evaluating survival outcomes of patients with SMZL according to the treatment received. read more here.
Keywords: population based; splenic marginal; marginal zone; zone lymphoma ... See more keywords
Corrigendum: Adrenergic-mediated loss of splenic marginal zone B cells contributes to infection susceptibility after stroke
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DOI: 10.1038/ncomms16151
Abstract: This corrects the article DOI: 10.1038/ncomms15051. read more here.
Keywords: marginal zone; adrenergic mediated; loss splenic; corrigendum adrenergic ... See more keywords
Intestinal angioedema caused by an acquired C1 esterase inhibitor deficiency associated with underlying splenic marginal zone lymphoma
Sign Up to like & getrecommendations! Published in 2021 at "Baylor University Medical Center Proceedings"
DOI: 10.1080/08998280.2021.1885277
Abstract: Abstract A 75-year-old woman presented with recurrent abdominal pain and vomiting for 1 year and was later found to have splenomegaly and pancytopenia. This case report depicts a clinical picture of intestinal angioedema, a challenging… read more here.
Keywords: intestinal angioedema; acquired esterase; deficiency associated; esterase inhibitor ... See more keywords
Risk-tailored treatment of splenic marginal zone lymphoma.
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DOI: 10.1097/cad.0000000000001165
Abstract: Splenic marginal zone lymphoma (SMZL) is a rare lymphoproliferative disease involving B-cells and affecting elderly patients. SMZL plague peripheral blood and bone marrow, spleen. Lymph nodes are generally spared. SMZL is due to a protracted… read more here.
Keywords: treatment; splenic marginal; risk; lymphoma ... See more keywords
Anti-CD20 rechallenge with ofatumumab in relapsed/refractory splenic marginal zone lymphoma: the MORE trial
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DOI: 10.1182/bloodadvances.2022007138
Abstract: Splenic marginal-zone lymphoma (SMZL) accounts for , 2% of lymphoid neoplasms. 1 Treatment is indicated for progressive and symptomatic splenomegaly and for cytopenias. 2,3 The options include splenectomy, chemotherapy, rituximab with or without chemotherapy, and… read more here.
Keywords: anti cd20; relapsed refractory; splenic marginal; marginal zone ... See more keywords
Unraveling the genetics of transformed splenic marginal zone lymphoma.
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DOI: 10.1182/bloodadvances.2022009415
Abstract: The genetic mechanisms associated with splenic marginal zone lymphoma transformation (SMZL-T) are not well defined. We studied 41 SMZL patients that eventually underwent large B-cell lymphoma transformation. Tumor material was obtained only at diagnosis (9… read more here.
Keywords: splenic marginal; transformation; marginal zone; zone lymphoma ... See more keywords
Toll-like receptor expression and function differ between splenic marginal zone B cell lymphoma and splenic diffuse red pulp B cell lymphoma
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DOI: 10.18632/oncotarget.25283
Abstract: In splenic marginal zone lymphoma (SMZL), specific and functional Toll-like Receptor (TLR) patterns have been recently described, suggesting their involvement in tumoral proliferation. Splenic diffuse red pulp lymphoma with villous lymphocytes (SDRPL) is close to… read more here.
Keywords: marginal zone; expression; splenic marginal; smzl ... See more keywords
The Splenic Marginal Zone in Children Is Characterized by a Subpopulation of CD27-Negative, Lowly IGHV-Mutated B Cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.825619
Abstract: Young children and older adults suffer from enhanced susceptibility to infections with blood-borne pathogens. An essential step towards immunity is the establishment of a splenic marginal zone (sMZ), which is immature at below 2 years… read more here.
Keywords: age; smz; smz cells; marginal zone ... See more keywords
Macrophage Depletion Mitigates Platelet Aggregate Formation in Splenic Marginal Zone and Alleviates LPS-Associated Thrombocytopenia in Rats
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DOI: 10.3389/fmed.2019.00300
Abstract: Sepsis is often accompanied with thrombocytopenia partly due to platelet sequestration in the lung and liver. The spleen can store up to one-third of circulating platelets and can also significantly affect platelet transfusion outcomes by… read more here.
Keywords: marginal zone; splenic marginal; associated thrombocytopenia; platelet ... See more keywords
Identification of a Splenic Marginal Zone Lymphoma Signature: Preliminary Findings With Diagnostic Potential
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DOI: 10.3389/fonc.2020.00640
Abstract: Splenic marginal zone lymphoma (SMZL) is a rare, indolent non-Hodgkin's lymphoma that affects 0. 13 per 100,000 persons annually. Overall survival of SMZL is estimated to reach 8–11 years in most cases, but up to… read more here.
Keywords: marginal zone; lymphoma; zone lymphoma; signature ... See more keywords
Identification of a Cancer-Predisposing Germline POT1 p.Ile49Metfs*7 Variant by Targeted Sequencing of a Splenic Marginal Zone Lymphoma
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DOI: 10.3390/genes13040591
Abstract: Germline disruptive variants in Protection of Telomeres 1 (POT1) predispose to a wide variety of cancers, including melanoma, chronic lymphocytic leukemia (CLL), Hodgkin lymphoma, myeloproliferative neoplasms, and glioma. We report the first case of splenic… read more here.
Keywords: pot1; lymphoma; germline pot1; variant ... See more keywords