Thrombocytopenia, splenomegaly, and periportal fibrosis in a migrant
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Hematology"
DOI: 10.1007/s00277-022-04838-3
Abstract: Dear Editor, Hepatosplenic schistosomiasis (HSS) is an underdiagnosed complication of chronic schistosomal infection which can lead to severe portal hypertensive complications if left untreated. We present a case of thrombocytopenia and splenomegaly secondary to undiagnosed… read more here.
Keywords: thrombocytopenia splenomegaly; schistosomiasis; fibrosis; splenomegaly ... See more keywords
Splenectomy for the Treatment of Splenomegaly in People Living with HIV: An Uncommon Complication.
Sign Up to like & getrecommendations! Published in 2025 at "Surgical infections"
DOI: 10.1089/sur.2025.003
Abstract: Objective: The objective of this study was to describe the clinical and microbiologic characteristics of adult patients with HIV infection and splenomegaly treated with splenectomy. Methods: We conducted a retrospective study, including patients with the… read more here.
Keywords: treatment; splenomegaly; treatment splenomegaly; splenomegaly people ... See more keywords
Laparoscopic splenectomy for a wandering spleen with resultant splenomegaly and gastric varices
Sign Up to like & getrecommendations! Published in 2020 at "ANZ Journal of Surgery"
DOI: 10.1111/ans.15737
Abstract: A wandering spleen is a rare entity, defined as splenic ectopy as a result of an absence or malformation of the splenic ligamentous attachments due to abnormalities of the dorsal mesogastrium at birth. This condition… read more here.
Keywords: torsion; abdominal pain; wandering spleen; splenomegaly ... See more keywords
Massive splenomegaly due to concurrent primary Epstein-Barr virus and cytomegalovirus infection in a patient on adalimumab
Sign Up to like & getrecommendations! Published in 2017 at "BMJ Case Reports"
DOI: 10.1136/bcr-2017-220184
Abstract: A 32-year-old man who was receiving adalimumab for seronegative rheumatoid arthritis presented with a 4-week history of fever, night sweats, fatigue, myalgias and diarrhoea. On examination, he had obvious splenomegaly but no lymphadenopathy or pharyngitis.… read more here.
Keywords: epstein barr; virus cytomegalovirus; barr virus; massive splenomegaly ... See more keywords
Effects of Splenomegaly in Children with Sickle Cell Anemia Treated with Hydroxyurea: Secondary Analysis of the Sphere Trial
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DOI: 10.1182/blood-2024-208408
Abstract: Introduction: Sickle cell anemia (SCA) typically causes splenic dysfunction and atrophy early in life, but in sub-Saharan Africa, many children have persistent splenomegaly that can lead to splenic sequestration and hypersplenism with recurrent cytopenias. We… read more here.
Keywords: irr; splenomegaly; hydroxyurea; intermittent ... See more keywords
A Rare Case of Warm Autoimmune Hemolytic Anemia and Massive Splenomegaly in Uncontrolled Grave's Disease
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DOI: 10.1182/blood-2024-211843
Abstract: Background: Autoimmune hemolytic anemia (AIHA) occurs when a person's immune system produces autoantibodies that attack their red blood cells, leading to their destruction. Warm AIHA, the most common form of AIHA, is caused by antibodies… read more here.
Keywords: history; splenomegaly; warm aiha; aiha ... See more keywords
Splenomegaly patterns and clinical impact in African children with sickle cell anemia on hydroxyurea treatment
Sign Up to like & getrecommendations! Published in 2025 at "Blood"
DOI: 10.1182/blood-2025-2971
Abstract: Introduction. Splenomegaly is a challenging complication for children with sickle cell anemia (SCA) in sub-Saharan Africa, with little experience gained from high-income countries where splenic infarction and involution occur early in life. The etiology, persistence,… read more here.
Keywords: treatment; splenomegaly; hydroxyurea; children sickle ... See more keywords
Hyperimmune malarial splenomegaly in a malaria-endemic area of southwest Burkina Faso: case of Bobo-Dioulasso
Sign Up to like & getrecommendations! Published in 2024 at "BMC Infectious Diseases"
DOI: 10.1186/s12879-024-09671-9
Abstract: Hyperreactive malarial splenomegaly (HMS) is one of the main causes of massive splenomegaly in malaria-endemic zones. Diagnosis is often challenging in Bobo-Dioulasso. This study aimed to describe the clinical and socio-demographic profile, and the reasons… read more here.
Keywords: burkina faso; splenomegaly; splenomegaly malaria; hms ... See more keywords
Comparison of thrombocytopenia and splenomegaly in locally advanced rectal cancer patients receiving total neoadjuvant therapy with and without immunotherapy.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2025.43.16_suppl.e15637
Abstract: e15637 Background: Thrombocytopenia is one of the main adverse effects of oxaliplatin-based chemotherapy, probably due to the hepatic sinusoidal obstruction syndrome and splenomegaly. The integration of PD-1 inhibitors with oxaliplatin-based total neoadjuvant therapy (TNT) has… read more here.
Keywords: cancer; splenomegaly; thrombocytopenia; immunotherapy ... See more keywords
Skin maculae, chronic diarrhea, cachexia, and splenomegaly—Late presentation of the first autochthonous case of visceral leishmaniasis in Tanzania
Sign Up to like & getrecommendations! Published in 2021 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0008925
Abstract: A 20-year-old man from Simanjiro district in northern Tanzania presented with a 3-year history of splenomegaly, fatigue, cachexia, skin maculae, and recent onset of watery diarrhea at Kilimanjaro Christian Medical Centre (KCMC) in Northern Tanzania.… read more here.
Keywords: leishmaniasis; cachexia; case; tanzania ... See more keywords
Short-term administration of JAK2 inhibitors reduces splenomegaly in mouse models of β-thalassemia intermedia and major
Sign Up to like & getrecommendations! Published in 2018 at "Haematologica"
DOI: 10.3324/haematol.2017.181511
Abstract: b-thalassemia is one of the most common congenital red blood cell (RBC) disorders characterized by limited bglobin synthesis and ineffective erythropoiesis. Based on the requirements for blood transfusion, the disease can be classified as non-transfusion… read more here.
Keywords: supplementary figure; figure; online supplementary; transfusion ... See more keywords