Abstract LB-244: A proteomics validated pipeline for detection of differential and tumor-specific splice events
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Research"
DOI: 10.1158/1538-7445.am2020-lb-244
Abstract: Splicing dysregulation is a common feature of cancer, and may produce tumor specific proteins that have altered function or antigenicity. While many tools are available to detect splicing in RNAseq data, robust methods for translating… read more here.
Keywords: splice events; detection; tumor specific; pipeline ... See more keywords
Analysis of Pathogenic Pseudoexons Reveals Novel Mechanisms Driving Cryptic Splicing
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DOI: 10.3389/fgene.2021.806946
Abstract: Understanding pre-mRNA splicing is crucial to accurately diagnosing and treating genetic diseases. However, mutations that alter splicing can exert highly diverse effects. Of all the known types of splicing mutations, perhaps the rarest and most… read more here.
Keywords: splice events; splicing; splice; deep intronic ... See more keywords