Multiplexed primer extension sequencing: A targeted RNA-seq method that enables high-precision quantitation of mRNA splicing isoforms and rare pre-mRNA splicing intermediates.
Sign Up to like & getrecommendations! Published in 2019 at "Methods"
DOI: 10.1016/j.ymeth.2019.05.013
Abstract: The study of pre-mRNA splicing has been greatly aided by the advent of RNA sequencing (RNA-seq), which enables the genome-wide detection of discrete splice isoforms. Quantification of these splice isoforms requires analysis of splicing informative… read more here.
Keywords: mrna splicing; rna seq; pre mrna; splice isoforms ... See more keywords
Specific presynaptic functions require distinct Drosophila Cav2 splice isoforms
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DOI: 10.1101/2024.06.14.598978
Abstract: The multiplicity of neural circuits that accommodate the sheer infinite number of computations conducted by brains requires diverse synapse and neuron types. At many vertebrate synapses release probability and other aspects of presynaptic function are… read more here.
Keywords: release; drosophila cav2; splice isoforms; cav2 ... See more keywords
Mechanism and function of CEACAM1 splice isoforms
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DOI: 10.1111/eci.14350
Abstract: Alternative splicing is a fundamental mechanism in the postâtranscriptional regulation of genes. The multifunctional transmembrane glycoprotein receptor carcinoembryonic antigenârelated cell adhesion molecule 1 (CEACAM1) undergoes extensive alternative splicing to allow for tunable functions in cell… read more here.
Keywords: ceacam1; function ceacam1; mechanism function; splice isoforms ... See more keywords