CpG Methylation-Driven Pleiotropic Spliced Isoforms of PRSS3 Facilitate Gastric Intratumor Heterogeneity and Metastasis.
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DOI: 10.1111/cas.70227
Abstract: Investigating the phenotypic contribution of gene‐spliced isoforms to tumor cellular heterogeneity can facilitate the development of innovative strategies for precision medicine. Serine protease 3 (PRSS3), a trypsin‐like protease with four spliced variants (PRSS3‐SVs: PRSS3‐V1 to… read more here.
Keywords: spliced isoforms; prss3; methylation; prss3 svs ... See more keywords