Novel spliced variants of OCT4, OCT4C and OCT4C1, with distinct expression patterns and functions in pluripotent and tumor cell lines.
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DOI: 10.1016/j.ejcb.2017.03.009
Abstract: OCT4 is a major regulator of pluripotency which has several spliced variants and expressed pseudogenes. Here, we are reporting the existence of two additional novel spliced variants of OCT4, OCT4C and OCT4C1, which lack Exon1… read more here.
Keywords: variants oct4; oct4c oct4c1; novel spliced; spliced variants ... See more keywords
Insights into the structural perturbations of spliced variants of CD44: a modeling and simulation approach
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2016.1142476
Abstract: Transient interactions between cancer stem cells and components of the tumor microenvironment initiate various signaling pathways crucial for carcinogenesis. Predominant hyaluronan (HA) receptor, CD44 is structurally and functionally one of the most variable cell surface… read more here.
Keywords: simulation approach; variants cd44; spliced variants; cd44v10 ... See more keywords