A two-step approach for sequencing spliceosome-related genes as a complementary diagnostic assay in MDS patients with ringed sideroblasts.
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DOI: 10.1016/j.leukres.2017.01.031
Abstract: Our study aimed to analyze the presence of mutations in SF3B1 and other spliceosome-related genes in myelodysplastic syndromes with ringed sideroblasts (MDS-RS) by combining conventional Sanger and next-generation sequencing (NGS) methods, and to determine the… read more here.
Keywords: spliceosome related; step; ringed sideroblasts; related genes ... See more keywords
Significance of Spliceosome-Related Genes in the Prediction of Prognosis and Treatment Strategies for Lung Adenocarcinoma
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DOI: 10.1155/2022/1753563
Abstract: Background The leading cause of cancer-related fatalities globally is lung cancer; lung adenocarcinoma (LUAD) is the most common histological type in it. The spliceosome plays an important role in a majority of malignancies. However, it… read more here.
Keywords: prognosis; treatment; spliceosome related; related genes ... See more keywords