Neo-Splicetopes in Tumor Therapy: A Lost Case?
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DOI: 10.3389/fimmu.2022.849863
Abstract: Proteasome generates spliced peptides by ligating two distant cleavage products in a reverse proteolysis reaction. The observation that CD8+ T cells recognizing a spliced peptide induced T cell rejection in a melanoma patient following adoptive… read more here.
Keywords: splicetopes tumor; spliced peptides; tumor therapy; therapy lost ... See more keywords