The Role of Alternative Splicing in Cancer: Regulatory Mechanism, Therapeutic Strategy, and Bioinformatics Application.
Sign Up to like & getrecommendations! Published in 2022 at "DNA and cell biology"
DOI: 10.1089/dna.2022.0322
Abstract: [Formula: see text] Alternative splicing (AS) can generate distinct transcripts and subsequent isoforms that play differential functions from the same pre-mRNA. Recently, increasing numbers of studies have emerged, unmasking the association between AS and cancer.… read more here.
Keywords: role alternative; biology; cancer regulatory; alternative splicing ... See more keywords
The Cancer Spliceome: Reprograming of Alternative Splicing in Cancer
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2018.00080
Abstract: Alternative splicing allows for the expression of multiple RNA and protein isoforms from one gene, making it a major contributor to transcriptome and proteome diversification in eukaryotes. Advances in next generation sequencing technologies and genome-wide… read more here.
Keywords: spliceome reprograming; splicing cancer; physiology; cancer ... See more keywords