The alternative splicing landscape of infarcted mouse heart identifies isoform level therapeutic targets
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Data"
DOI: 10.1038/s41597-024-03998-3
Abstract: Alternative splicing is an important process that contributes to highly diverse transcripts and protein products, which can affect the development of disease in various organisms. Cardiovascular disease (CVD) represents one of the greatest global threats… read more here.
Keywords: alternative splicing; heart; splicing landscape; mouse heart ... See more keywords
The HTLV-1 viral oncoproteins Tax and HBZ reprogram the cellular mRNA splicing landscape
Sign Up to like & getrecommendations! Published in 2021 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1009919
Abstract: Viral infections are known to hijack the transcription and translation of the host cell. However, the extent to which viral proteins coordinate these perturbations remains unclear. Here we used a model system, the human T-cell… read more here.
Keywords: tax; tax hbz; mrna splicing; splicing landscape ... See more keywords