Novel Intronic Mutations of TBK1 Promote Aberrant Splicing Modes in Amyotrophic Lateral Sclerosis
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DOI: 10.3389/fnmol.2022.691534
Abstract: TANK-binding kinase 1 (TBK1) has been identified as a causative gene of amyotrophic lateral sclerosis (ALS) in the Caucasian population in 2015. Here, we sequenced for TBK1 variants in a cohort of 15 familial ALS… read more here.
Keywords: splicing modes; lateral sclerosis; novel intronic; amyotrophic lateral ... See more keywords