WT1 Alternative Splicing: Role of Its Isoforms in Neuroblastoma
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DOI: 10.1007/s12031-017-0930-0
Abstract: Wilms tumor 1 (WT1), a tumor suppressor gene, was originally identified in the homonymous renal neoplasm but is also involved in other cancers. Its function is still unclear, since it acts both as a pro-… read more here.
Keywords: wt1 alternative; role isoforms; splicing role; isoforms neuroblastoma ... See more keywords
Alternative Splicing Role in New Therapies of Spinal Muscular Atrophy
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DOI: 10.3390/genes12091346
Abstract: It has been estimated that 80% of the pre-mRNA undergoes alternative splicing, which exponentially increases the flow of biological information in cellular processes and can be an attractive therapeutic target. It is a crucial mechanism… read more here.
Keywords: spinal muscular; splicing role; muscular atrophy; role new ... See more keywords