Split-Dose Bowel Preparation Reduces the Need for Early Repeat Colonoscopy Without Improving Adenoma Detection Rate
Sign Up to like & getrecommendations! Published in 2017 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-017-4877-3
Abstract: Background and AimsSplit-dose bowel preparation is associated with improved mucosal visualization and patient tolerance, becoming a standard of care. However, quality measures data associated with this preparation are limited. At our academic tertiary-care facility, we… read more here.
Keywords: bowel preparation; split dose; preparation; rate ... See more keywords
Split-Dose Administration Enhances Immune Responses Elicited by a mRNA/Lipid Nanoparticle Vaccine Expressing Respiratory Syncytial Virus F Protein.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.2c00635
Abstract: mRNA vaccines have recently received significant attention due to their role in combating the SARS-CoV-2 pandemic. As a platform, mRNA vaccines have been shown to elicit strong humoral and cellular immune responses with acceptable safety… read more here.
Keywords: split dose; syncytial virus; immune responses; lipid nanoparticle ... See more keywords
MANDATORY VS. OPTIONAL SPLIT-DOSE BOWEL PREPARATION FOR MORNING COLONOSCOPIES: A PRAGMATIC NON-INFERIORITY RANDOMIZED CONTROLLED TRIAL.
Sign Up to like & getrecommendations! Published in 2023 at "Endoscopy"
DOI: 10.1055/a-2070-5561
Abstract: BACKGROUND We compared the effectiveness of optional split-dose bowel preparation (SDBP) to mandatory SDBP for morning colonoscopies in usual clinical practice. METHODS Adult patients undergoing outpatient early morning (8:00am-10:30am) and late morning (10:30am-12:00pm) colonoscopies were… read more here.
Keywords: split dose; bowel preparation; morning colonoscopies; mandatory sdbp ... See more keywords
Fractionated FLASH radiation in xenografted lung tumors induced FLASH effect at a split dose of 2 Gy.
Sign Up to like & getrecommendations! Published in 2023 at "International journal of radiation biology"
DOI: 10.1080/09553002.2023.2194403
Abstract: PURPOSE To explore the minimum split dose of FLASH radiotherapy (FLASH). MATERIAL AND METHODS Lungs of nude mice were used to verify the capacity of normal tissue sparing of FLASH, while tumor-bearing nude mice were… read more here.
Keywords: flash effect; split dose; effect; tumor ... See more keywords
Inadequate Bowel Cleansing Efficacy of Split-dose Polyethylene Glycol for Colonoscopy in Type 2 Diabetic Patients: A Prospective and Blinded Study
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Gastroenterology"
DOI: 10.1097/mcg.0000000000000536
Abstract: Background/Aims: Split-dose polyethylene glycol (PEG) is considered a standard bowel preparation regimen for colonoscopy in the general population. However, it is not clear whether the regimen is optimal for colonoscopy in diabetic patients. The aim… read more here.
Keywords: diabetic patients; split dose; preparation; bowel preparation ... See more keywords
An Automated Inpatient Split-dose Bowel Preparation System Improves Colonoscopy Quality and Reduces Repeat Procedures
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Gastroenterology"
DOI: 10.1097/mcg.0000000000000849
Abstract: Background/Goals: Inpatient colonoscopy preparations are often inadequate, compromising patient safety and procedure quality, while resulting in greater hospital costs. The aims of this study were to: (1) design and implement an electronic inpatient split-dose bowel… read more here.
Keywords: quality; bowel preparation; split dose; dose bowel ... See more keywords
Same-day Versus Split-dose Bowel Preparation Before Colonoscopy: A Meta-analysis
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Gastroenterology"
DOI: 10.1097/mcg.0000000000000860
Abstract: Background: Split-dose regimens (SpDs) were recommended as a first choice for bowel preparation, whereas same-day regimens (SaDs) were recommended as an alternative; however, randomized trials compared them with mixed results. The meta-analysis was aimed at… read more here.
Keywords: bowel preparation; analysis; split dose; spds ... See more keywords
PWE-036 Polyethylene glycol purgatives prior to small bowel capsule endoscopy improve distal small bowel visualisation
Sign Up to like & getrecommendations! Published in 2019 at "Gut"
DOI: 10.1136/gutjnl-2019-bsgabstracts.323
Abstract: Introduction Bowel purgatives are common practice prior to small bowel capsule endoscopy (SBCE). The use of Polyethylene glycol (PEG) laxatives is suggested to improve SB visualisation quality and diagnostic yield [Kotwal, Eur J Gastro Hep… read more here.
Keywords: split dose; small bowel; bowel; visualisation ... See more keywords
Efficacy and Safety of Single-Dose Versus Split-Dose Mecapegfilgrastim with Etoposide for Autologous Peripheral Blood Stem Cell Mobilization: A Prospective, Randomized Clinical Trial
Sign Up to like & getrecommendations! Published in 2024 at "Blood"
DOI: 10.1182/blood-2024-202870
Abstract: High-dose chemotherapy combined with autologous hematopoietic stem cell transplantation (auto-HSCT) is a well-established consolidation treatment for lymphoma and multiple myeloma, reducing relapse risk and improving survival. Effective mobilization of peripheral blood stem cells (PBSC), measured… read more here.
Keywords: single dose; dose group; split dose; mobilization ... See more keywords
Patterns of split-dose gemcitabine and cisplatin (GC) use in patients with locally advanced or metastatic urothelial carcinoma (la/mUC): Results of a 10-country physician survey.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2025.43.5_suppl.699
Abstract: 699 Background: Gemcitabine + cisplatin (GC) is a highly effective treatment for la/mUC. For patients who are ineligible for standard GC, split-dose GC is a promising alternative. This study aimed to provide insights into the… read more here.
Keywords: treatment; split; practice; split dose ... See more keywords
Multicenter Phase II Clinical Trial of Gemcitabine and Cisplatin as Neoadjuvant Chemotherapy for Patients With High-Grade Upper Tract Urothelial Carcinoma
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.22.00763
Abstract: PURPOSE Neoadjuvant chemotherapy (NAC) has proven survival benefits for patients with invasive urothelial carcinoma of the bladder, yet its role for upper tract urothelial carcinoma (UTUC) remains undefined. We conducted a multicenter, single-arm, phase II… read more here.
Keywords: urothelial carcinoma; neoadjuvant chemotherapy; split dose; upper tract ... See more keywords