Split First Dose Administration of Intravenous Daratumumab for the Treatment of Multiple Myeloma (MM): Clinical and Population Pharmacokinetic Analyses
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DOI: 10.1007/s12325-020-01247-8
Abstract: Introduction Daratumumab, a human immunoglobulin Gκ monoclonal antibody targeting CD38, is approved as monotherapy and in combination with standard-of-care regimens for multiple myeloma. In clinical studies, the median durations of the first, second, and subsequent… read more here.
Keywords: first dose; treatment; multiple myeloma; daratumumab ... See more keywords
Systolic ejection click versus split first heart sound: Are our ears deceiving us?
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DOI: 10.1111/chd.12460
Abstract: OBJECTIVE Bicuspid aortic valve (BAV) disease is associated with potential lifetime complications, but auscultation of a BAV click is commonly missed or mistaken for a benign split first heart sound. Our objective was to determine… read more here.
Keywords: heart sound; first heart; heart; split first ... See more keywords